User talk:Johan sunryd/sandbox 1 - Revision history

Johan Sunryd: Molecular Playground/ ER mannosidases 1

Johan Sunryd — Fri, 30 Apr 2010 02:07:08 GMT

Molecular Playground/ ER mannosidases 1

←Older revision		Revision as of 02:07, 30 April 2010
Line 1:		Line 1:
-	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.	+	Alpha-mannosidases I(ERMan1) is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.


	{{Clear}}		{{Clear}}
	<applet load='1X9D' size='[450,338]' frame='true' align='right'		<applet load='1X9D' size='[450,338]' frame='true' align='right'
-	caption='ERMan1 (1X9D)' scene='~~User~~:~~Johan_Sunryd~~/~~Sandbox_1~~/~~Loadedfrompdb~~/4'/>	+	caption='ERMan1 (1X9D)' <scene name='User_talk:Johan_sunryd/sandbox_1/Catalytic_site_of_erman_1/1'>TextToBeDisplayed</scene>

	=== Catalytic Site ===		=== Catalytic Site ===

Johan Sunryd: Molecular Playground/ERMan1

Johan Sunryd — Fri, 30 Apr 2010 02:02:54 GMT

Molecular Playground/ERMan1

←Older revision		Revision as of 02:02, 30 April 2010
Line 1:		Line 1:
-
	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.		Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.

Johan Sunryd at 01:55, 30 April 2010

Johan Sunryd — Fri, 30 Apr 2010 01:55:59 GMT

←Older revision		Revision as of 01:55, 30 April 2010
Line 1:		Line 1:
-

	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.		Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.
Line 15:		Line 14:


-	Molecular Playground banner: A catalytic timer for protein degradation.	+	"Molecular Playground banner: A catalytic timer for protein degradation."

Johan Sunryd at 02:03, 26 April 2010

Johan Sunryd — Mon, 26 Apr 2010 02:03:24 GMT

←Older revision		Revision as of 02:03, 26 April 2010
Line 1:		Line 1:
-	~~[<scene name='User_talk:Johan_sunryd/sandbox_1/Side_view_of_erman1/1'>TextToBeDisplayed</scene>]~~	+

	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.		Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.

Johan Sunryd at 02:00, 26 April 2010

Johan Sunryd — Mon, 26 Apr 2010 02:00:54 GMT

←Older revision		Revision as of 02:00, 26 April 2010
Line 1:		Line 1:
-	[~~[Image~~:~~intactModelLargeText.jpg\|frame\|ER Man~~ 1]]	+	[<scene name='User_talk:Johan_sunryd/sandbox_1/Side_view_of_erman1/1'>TextToBeDisplayed</scene>]

	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.		Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.
Line 12:		Line 12:


-	The spinning protein (<scene name='~~User~~:~~Lynmarie_K_Thompson~~/~~Sandbox_1~~/~~Loadedfrompdb~~/4'>~~Initial view~~</scene>) ) is a highlight of the catalytic residues of ERMan1.	+	The spinning protein (<scene name='User_talk:Johan_sunryd/sandbox_1/Erman1_full_length/1'>TextToBeDisplayed</scene>) ) is a highlight of the catalytic residues of ERMan1.


	Molecular Playground banner: A catalytic timer for protein degradation.		Molecular Playground banner: A catalytic timer for protein degradation.

Johan Sunryd at 01:39, 26 April 2010

Johan Sunryd — Mon, 26 Apr 2010 01:39:25 GMT

←Older revision		Revision as of 01:39, 26 April 2010
Line 1:		Line 1:
-
	[[Image:intactModelLargeText.jpg\|frame\|ER Man 1]]		[[Image:intactModelLargeText.jpg\|frame\|ER Man 1]]

-	ER Mannosidase 1 is a type II ER membrane protein that. EMechanism of class 1 (glycosylhydrolase family 47) Alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.	+	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47 group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as indicators of how well a client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein can be targeted for degradation by other ER proteins.
-		+
-	Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47, group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as ~~a indicator~~ of how ~~wella~~ client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein ~~will~~ be ~~detected as misfolded~~ by other ER proteins.	+

Johan Sunryd: New page: ER Man 1 ER Mannosidase 1 is a type II ER membrane protein that. EMechanism of class 1 (glycosylhydrolase family 47) Alpha-mannosidases involved ...

Johan Sunryd — Mon, 26 Apr 2010 01:34:35 GMT

New page: ER Man 1 ER Mannosidase 1 is a type II ER membrane protein that. EMechanism of class 1 (glycosylhydrolase family 47) Alpha-mannosidases involved ...

New page

[[Image:intactModelLargeText.jpg|frame|ER Man 1]]

ER Mannosidase 1 is a type II ER membrane protein that. EMechanism of class 1 (glycosylhydrolase family 47) Alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control.

Alpha-mannosidases I is a human protein that reside in the endoplasmic reticulum(ER) lumen. ERMan1 is part of the class 1 glycosylhydrolase family 47, group of proteins and sports a Tim-barrel fold. In the ER N-linked glycans are used as a indicator of how wella client protein is folded. ERMan1 functions by slowly trimming N-linked glycans, giving the protein at hand a defined window of time before the client protein will be detected as misfolded by other ER proteins.

{{Clear}}
<applet load='1X9D' size='[450,338]' frame='true' align='right'
caption='ERMan1 (1X9D)' scene='User:Johan_Sunryd/Sandbox_1/Loadedfrompdb/4'/>

=== Catalytic Site ===

The spinning protein (<scene name='User:Lynmarie_K_Thompson/Sandbox_1/Loadedfrompdb/4'>Initial view</scene>) ) is a highlight of the catalytic residues of ERMan1.

Molecular Playground banner: A catalytic timer for protein degradation.