Thioredoxin Reductase
From Proteopedia
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[[Image:1cl0.png|left|200px|thumb|Crystal Structure of Thioredoxin Reductase [[1cl0]]]] | [[Image:1cl0.png|left|200px|thumb|Crystal Structure of Thioredoxin Reductase [[1cl0]]]] | ||
| - | {{STRUCTURE_1cl0| PDB=1cl0 | SIZE= | + | {{STRUCTURE_1cl0| PDB=1cl0 | SIZE=400| SCENE=Thioredoxin_Reductase/Cv/1 |right|CAPTION=Thioredoxin Reductase complex with FAD [[1cl0]] }} |
[[Thioredoxin Reductase]] (TrxR) is an enzyme which reduces thioredoxin using NADPH. TrxR-2 is mitochondrial. The images at the left and at the right correspond to one representative TrxR, ''i.e.'' the crystal structure of Thioredoxin Reductase from ''Eschericia coli'' ([[1cl0]]). For more details see [[User:Sarah Abdalla/Thioredoxin Reductase]]. | [[Thioredoxin Reductase]] (TrxR) is an enzyme which reduces thioredoxin using NADPH. TrxR-2 is mitochondrial. The images at the left and at the right correspond to one representative TrxR, ''i.e.'' the crystal structure of Thioredoxin Reductase from ''Eschericia coli'' ([[1cl0]]). For more details see [[User:Sarah Abdalla/Thioredoxin Reductase]]. | ||
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== 3D Structures of Thioredoxin Reductase == | == 3D Structures of Thioredoxin Reductase == | ||
| - | ''Update | + | ''Update December 2011'' |
===TrxR=== | ===TrxR=== | ||
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[[2zz0]], [[2zzb]], [[2zzc]] – hTrxR-1 (mutant)+FAD<br /> | [[2zz0]], [[2zzb]], [[2zzc]] – hTrxR-1 (mutant)+FAD<br /> | ||
[[2j3n]] – hTrxR-1+FAD+NADPH<br /> | [[2j3n]] – hTrxR-1+FAD+NADPH<br /> | ||
| + | [[3qfa]] [[3qfb]] - hTrxR-1 (mutant) +FAD+ Trx<br /> | ||
[[3itj]] – yTrxR-1+FAD <br /> | [[3itj]] – yTrxR-1+FAD <br /> | ||
[[3dh9]], [[3dgh]] – DmTrxR-1+FAD<br /> | [[3dh9]], [[3dgh]] – DmTrxR-1+FAD<br /> | ||
Revision as of 10:05, 20 December 2011
Thioredoxin Reductase (TrxR) is an enzyme which reduces thioredoxin using NADPH. TrxR-2 is mitochondrial. The images at the left and at the right correspond to one representative TrxR, i.e. the crystal structure of Thioredoxin Reductase from Eschericia coli (1cl0). For more details see User:Sarah Abdalla/Thioredoxin Reductase.
3D Structures of Thioredoxin Reductase
Update December 2011
TrxR
1cl0, 1tde, 1trb – EcTrxR+FAD – Eschericia coli
1tdf - EcTrxR+FAD+NADPH
1f6m - EcTrxR (mutant)+Trx-1+FAD+AADPH
1h6v – rTrxR (mutant)+FAD+NADPH – rat
1vdc – TrxR+FAD – Arabidopsis thaliana
2a87 - TrxR+FAD+NADPH – Mycobacterium tuberculosis
3cty - TrxR+FAD – Thermoplasma acidophilum
3d8x - yTrxR+FAD+NADPH - yeast
2nvk - DmTrxR+FAD+NADPH – Drosophila melanogaster
2q0k, 2q0l - HpTrxR+FAD+NADPH – Helicobacter pylori
3ish - HpTrxR+FAD
2q7v - TrxR+FAD – Deinococcus radiodurans
3r9u – TrxR – Campylobacter jejuni
TrxR-1
2cfy – hTrxR-1+FAD – human
2zz0, 2zzb, 2zzc – hTrxR-1 (mutant)+FAD
2j3n – hTrxR-1+FAD+NADPH
3qfa 3qfb - hTrxR-1 (mutant) +FAD+ Trx
3itj – yTrxR-1+FAD
3dh9, 3dgh – DmTrxR-1+FAD
3ean, 3eao – rTrxR-1+FAD+NADPH
TrxR-2
1zdl, 1zkq – mTrxR-2+FAD+NADPH – mouse
3dgz – mTrxR-2+FAD
2whd – TrxR-2+FAD – Hordeum vulgare
TrxR-3
3f8d, 3f8p, 3f8r – TrxR-3 (mutant)+FAD – Sulfolobus solfataricus
3h8q – hTrxR-3 glutaredoxin domain
