Ras GTPase activating protein
From Proteopedia
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[[Image:2gqi.png|left|thumb|300px|NMR Structure of the Ras GTPase activating protein, [[2gqi]]]] | [[Image:2gqi.png|left|thumb|300px|NMR Structure of the Ras GTPase activating protein, [[2gqi]]]] | ||
{{STRUCTURE_2j05| right| PDB=2j05 | SCENE=|CAPTION= Human Ras GTPase activating protein dimer. SH3 domain, [[2j05]] }} | {{STRUCTURE_2j05| right| PDB=2j05 | SCENE=|CAPTION= Human Ras GTPase activating protein dimer. SH3 domain, [[2j05]] }} | ||
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Revision as of 08:02, 14 November 2012
Image:2gqi.png
NMR Structure of the Ras GTPase activating protein, 2gqi
Ras GTPase activating protein (RasGAP) inactivates Ras from its active GTP-bound form to its GDP-bound form. It is part of the mitogenic signal transmission via its N-terminal SH2-SH3-SH2 domains. The images on the left and right correspond to one representative RasGAP structure, i.e. the human RasGAP SH3 domain (2gqi).
3D Structures of Ras GTPase activating protein
2gqi – hRasGAP SH3 domain – human – NMR
2j05, 2j06 - hRasGAP SH3 domain
2gsb - hRasGAP SH2 domain – NMR
3bxj - hRasGAP SYNGAP fragment - rat
