Ras GTPase activating protein

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[[Ras GTPase activating protein]] (RasGAP) inactivates Ras from its active GTP-bound form to its GDP-bound form. It is part of the mitogenic signal transmission via its N-terminal SH2-SH3-SH2 domains. The images on the left and right correspond to one representative RasGAP structure, ''i.e.'' the human RasGAP SH3 domain ([[2gqi]]).
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[[Ras GTPase activating protein]] (RasGAP) inactivates Ras from its active GTP-bound form to its GDP-bound form. It is part of the mitogenic signal transmission via its N-terminal SH2-SH3-SH2 domains.
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Revision as of 11:33, 23 September 2014

Image:2gqi.png
NMR Structure of the Ras GTPase activating protein, 2gqi

Template:STRUCTURE 2j05
















Ras GTPase activating protein (RasGAP) inactivates Ras from its active GTP-bound form to its GDP-bound form. It is part of the mitogenic signal transmission via its N-terminal SH2-SH3-SH2 domains.

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3D Structures of Ras GTPase activating protein

Updated on 23-September-2014

2gqi, 2m51 – hRasGAP SH3 domain – human – NMR
2j05, 2j06, 4fss - hRasGAP SH3 domain
2gsb - hRasGAP SH2 domain – NMR
3bxj - hRasGAP SYNGAP fragment - rat

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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