TRNA-guanine transglycosylase

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'''tRNA-guanine transglycosylase''' (TGT) is involved in the post-transcriptional modification of tRNA. TGT is involved in the replacement of guanine-34 by queuine precursor (preQ1) in the anticodon of tRNA. In archaebacteria TGT (ATGT) catalyzes the introduction of archaeosin precursor (preQ0) into the D-loop of tRNA.
'''tRNA-guanine transglycosylase''' (TGT) is involved in the post-transcriptional modification of tRNA. TGT is involved in the replacement of guanine-34 by queuine precursor (preQ1) in the anticodon of tRNA. In archaebacteria TGT (ATGT) catalyzes the introduction of archaeosin precursor (preQ0) into the D-loop of tRNA.
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</StructureSection>
==3D structures of tRNA-guanine transglycosylase==
==3D structures of tRNA-guanine transglycosylase==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===TGT===
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*tRNA-guanine transglycosylase
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[[1pud]], [[1p0d]] – ZmTGT – ''Zymomonas mobilis''<BR />
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**[[1pud]], [[1p0d]] – ZmTGT – ''Zymomonas mobilis''<BR />
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[[1wkd]], [[1wke]], [[1wkf]], [[1ozm]], [[2oko]], [[2z1v]], [[2nso]], [[3bl3]], [[3hfy]], [[4gd0]], [[4h6e]], [[3unt]], [[3uvi]], [[4dxx]], [[4dy1]], [[4htb]], [[4ipp]], [[4jbr]] – ZmTGT (mutant)<BR />
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**[[1wkd]], [[1wke]], [[1wkf]], [[1ozm]], [[2oko]], [[2z1v]], [[2nso]], [[3bl3]], [[3hfy]], [[4gd0]], [[4h6e]], [[3unt]], [[3uvi]], [[4dxx]], [[4dy1]], [[4htb]], [[4ipp]], [[4jbr]] – ZmTGT (mutant)<BR />
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[[2ash]] – TGT – ''Thermotoga maritima''<BR />
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**[[2ash]] – TGT – ''Thermotoga maritima''<BR />
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===TGT complexes===
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*tRNA-guanine transglycosylase complexes
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[[1efz]], [[1pxg]], [[1ozq]], [[2z1x]], [[2nqz]], [[3bld]], [[4gcx]], [[4e2v]] – ZmTGT (mutant) + preQ1<BR />
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**[[1efz]], [[1pxg]], [[1ozq]], [[2z1x]], [[2nqz]], [[3bld]], [[4gcx]], [[4e2v]] – ZmTGT (mutant) + preQ1<BR />
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[[3bll]] – ZmTGT (mutant) + preQ1 derivative<BR />
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**[[3bll]] – ZmTGT (mutant) + preQ1 derivative<BR />
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[[1p0e]] – ZmTGT + preQ1<BR />
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**[[1p0e]] – ZmTGT + preQ1<BR />
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[[1p0b]], [[2qii]] – ZmTGT + preQ0<BR />
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**[[1p0b]], [[2qii]] – ZmTGT + preQ0<BR />
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[[2pwv]] – ZmTGT (mutant) + preQ0<BR />
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**[[2pwv]] – ZmTGT (mutant) + preQ0<BR />
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[[3blo]], [[4hqv]], [[4hsh]], [[4hvx]] – ZmTGT (mutant) + queuine<BR />
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**[[3blo]], [[4hqv]], [[4hsh]], [[4hvx]] – ZmTGT (mutant) + queuine<BR />
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[[1enu]], [[1f3e]] – ZmTGT + aminophthalhydrazide<BR />
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**[[1enu]], [[1f3e]] – ZmTGT + aminophthalhydrazide<BR />
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[[1r5y]], [[1q4w]], [[1q63]], [[1q65]], [[1q66]], [[1s38]], [[1s39]], [[1y5v]], [[1y5w]], [[1y5x]], [[2bbf]], [[2qzr]], [[3c2n]], [[3c2y]], [[3c2z]], [[3eos]], [[3eou]], [[3gc4]], [[1k4g]], [[1k4h]], [[3gc5]], [[3ge7]], [[3gev]] – ZmTGT + quinazoline inhibitor<BR />
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**[[1r5y]], [[1q4w]], [[1q63]], [[1q65]], [[1q66]], [[1s38]], [[1s39]], [[1y5v]], [[1y5w]], [[1y5x]], [[2bbf]], [[2qzr]], [[3c2n]], [[3c2y]], [[3c2z]], [[3eos]], [[3eou]], [[3gc4]], [[1k4g]], [[1k4h]], [[3gc5]], [[3ge7]], [[3gev]] – ZmTGT + quinazoline inhibitor<BR />
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[[1n2v]], [[2z1w]] – ZmTGT + pyridazine derivative<BR />
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**[[1n2v]], [[2z1w]] – ZmTGT + pyridazine derivative<BR />
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[[1q2r]], [[1q2s]] – ZmTGT + RNA<BR />
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**[[1q2r]], [[1q2s]] – ZmTGT + RNA<BR />
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[[2pot]], [[2pwu]], [[4h7z]] – ZmTGT (mutant) + guanine<BR />
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**[[2pot]], [[2pwu]], [[4h7z]] – ZmTGT (mutant) + guanine<BR />
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[[2z7k]], [[3rr4]], [[3tll]], [[4fr6]], [[4fsa]], [[4fr1]], [[4fps]], [[4gi4]], [[4giy]], [[4gkt]] – ZmTGT + benzoguanine derivative<BR />
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**[[2z7k]], [[3rr4]], [[3tll]], [[4fr6]], [[4fsa]], [[4fr1]], [[4fps]], [[4gi4]], [[4giy]], [[4gkt]] – ZmTGT + benzoguanine derivative<BR />
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[[3v0y]], [[3s1g]], [[3sm0]], [[4gg9]], [[4gh1]], [[4gh3]], [[4ghr]] – ZmTGT + benzohypoxanthine derivative<BR />
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**[[3v0y]], [[3s1g]], [[3sm0]], [[4gg9]], [[4gh1]], [[4gh3]], [[4ghr]] – ZmTGT + benzohypoxanthine derivative<BR />
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===ATGT===
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*Archaebacterial tRNA-guanine transglycosylase
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[[1iq8]] – PhATGT – ''Pyrococcus horikoshii''<BR />
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[[1it7]] – PhATGT + guanine<BR />
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[[1it8]] – PhATGT + preQ0<BR />
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[[1j2b]] – PhATGT + tRNA-Val<BR />
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**[[1iq8]] – PhATGT – ''Pyrococcus horikoshii''<BR />
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**[[1it7]] – PhATGT + guanine<BR />
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**[[1it8]] – PhATGT + preQ0<BR />
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**[[1j2b]] – PhATGT + tRNA-Val<BR />
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}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 11:53, 15 December 2014

Structure of tRNA-guanine transglycosylase complex with queuine precursor (PDB entry 1p0e)

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3D structures of tRNA-guanine transglycosylase

Updated on 15-December-2014

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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