Catenin

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Line 56: Line 56:
* α+β-CTN
* α+β-CTN
-
[[4ons]] - mCTN <br />
+
**[[4ons]] - mCTN <br />
* γ-CTN
* γ-CTN

Revision as of 09:16, 12 March 2015

Template:STRUCTURE 2z6g


Catenins (CTN) are proteins which make complexes with cadherin.

  • α-CTN links cadherin (CDH) and α-actinin, it is encoded by 3 genes: α-E-CTN (epithelial), α-T-CTN (membrane bound), and α-N-CTN (neuronal).
  • β-CTN is a subunit of the cadherin complex. It contains Armadillo repeats which are a pair of helices forming hairpin structure.
  • γ-CTN (or plakoglobin) is a component of desmosomes and contains armadillo repeats.
  • δ-CTN is expressed in the brain and contains 10 armadillo repeats.
  • p120 CTN is another member of the CTN family.

3D Structures of Catenin

Updated on 12-March-2015

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky

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