TRNA-guanine transglycosylase

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**[[3blo]], [[4hqv]], [[4hsh]], [[4hvx]] – ZmTGT (mutant) + queuine<BR />
**[[3blo]], [[4hqv]], [[4hsh]], [[4hvx]] – ZmTGT (mutant) + queuine<BR />
**[[1enu]], [[1f3e]] – ZmTGT + aminophthalhydrazide<BR />
**[[1enu]], [[1f3e]] – ZmTGT + aminophthalhydrazide<BR />
-
**[[1r5y]], [[1q4w]], [[1q63]], [[1q65]], [[1q66]], [[1s38]], [[1s39]], [[1y5v]], [[1y5w]], [[1y5x]], [[2bbf]], [[2qzr]], [[3c2n]], [[3c2y]], [[3c2z]], [[3eos]], [[3eou]], [[3gc4]], [[1k4g]], [[1k4h]], [[3gc5]], [[3ge7]], [[3gev]], [[4puj]], [[4puk]], [[4q4o]], [[4q4p]], [[4q4q]], [[4q4r]], [[4q4s]], [[4q8t]], [[4q4u]], [[4q8v]], [[4q8w]] – ZmTGT + quinazoline inhibitor<BR />
+
**[[1r5y]], [[1q4w]], [[1q63]], [[1q65]], [[1q66]], [[1s38]], [[1s39]], [[1y5v]], [[1y5w]], [[1y5x]], [[2bbf]], [[2qzr]], [[3c2n]], [[3c2y]], [[3c2z]], [[3eos]], [[3eou]], [[3gc4]], [[1k4g]], [[1k4h]], [[3gc5]], [[3ge7]], [[3gev]], [[4puj]], [[4puk]], [[4q4o]], [[4q4p]], [[4q4q]], [[4q4r]], [[4q4s]], [[4q8t]], [[4q4u]], [[4q8v]], [[4q8w]], [[5jxq]] – ZmTGT + quinazoline inhibitor<BR />
 +
**[[4q4m]] – ZmTGT + triazine inhibitor<BR />
**[[4pul]], [[4pum]], [[4q8o]], [[4q8p]], [[4q8q]] – ZmTGT (mutant) + quinazoline inhibitor<BR />
**[[4pul]], [[4pum]], [[4q8o]], [[4q8p]], [[4q8q]] – ZmTGT (mutant) + quinazoline inhibitor<BR />
**[[1n2v]], [[2z1w]] – ZmTGT + pyridazine derivative<BR />
**[[1n2v]], [[2z1w]] – ZmTGT + pyridazine derivative<BR />

Revision as of 09:03, 26 September 2016

Structure of tRNA-guanine transglycosylase complex with queuine precursor (PDB entry 1p0e)

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3D structures of tRNA-guanine transglycosylase

Updated on 26-September-2016

References

  1. Nonekowski ST, Garcia GA. tRNA recognition by tRNA-guanine transglycosylase from Escherichia coli: the role of U33 in U-G-U sequence recognition. RNA. 2001 Oct;7(10):1432-41. PMID:11680848
  2. Brenk R, Stubbs MT, Heine A, Reuter K, Klebe G. Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design. Chembiochem. 2003 Oct 6;4(10):1066-77. PMID:14523925 doi:10.1002/cbic.200300644

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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