Ribosomal protein S8

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(New page: Crystal Structure of Ribosomal protein S8 from 2zm6, chain H {{STRUCTURE_2zm6| PDB=2zm6 | SIZE=300| SCENE= |right|CAPTION=Ribosomal protein S8 fro...)
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[[Image:RPS8.png|left|200px|thumb|Crystal Structure of Ribosomal protein S8 from [[2zm6]], chain H]]
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<StructureSection load='1sei' size='350' side='right' scene='' caption='Ribosomal protein S8 (PDB code [[1sei]])'>
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{{STRUCTURE_2zm6| PDB=2zm6 | SIZE=300| SCENE= |right|CAPTION=Ribosomal protein S8 from [[2zm6]], chain H }}
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[[Ribosomal protein S8]] (RPS8) is one of the 21 proteins which belong to the 30S <scene name='Ribosomal_protein_S8/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It binds to 16S RRNA and interacts with spc operon mRNA<ref>PMID:1735715</ref>. In archaea the protein is named S8E (RPS8E).
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</StructureSection>
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[[Ribosomal protein S8]] (RPS8) is one of the 22 proteins which belong to the small subunit of the ribosome. It binds to 16S RRNA and interacts with spc operon mRNA. In archaea the protein is named S8E (RPS8E). The images at the left and at the right correspond to one representative RPS8, ''i.e.'' the crystal structure of Ribosomal protein S8 from ''Thermus thermophilus'' ([[2zm6]], chain H).
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== 3D Structures of Ribosomal protein S8 ==
== 3D Structures of Ribosomal protein S8 ==
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===RPS8===
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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[[1an7]] – TtRPS8 - ''Thermus thermophilus''<br />
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[[1sei]] – RPS8 – ''Geobacillus stearothermophilus''<br />
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[[2kcp]], [[2kcy]] – RPS8E – ''Methanothermobacter thermaututrophicus'' – NMR<br />
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[[2kco]] – RPS8E – ''Sulfolobus solfataricus'' - NMR
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===S8 in small ribosomal subunit===
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[[2zm6]], [[1n36]], [[1j5e]] - TtRPS5 in 30S ribosomal subunit+THX+16S RRNA – ''Thermus thermophilus''<br />
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[[2vqe]], [[2vqf]], [[2uuc]], [[2e5l]], [[2uu9]], [[2uua]], [[2uub]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+RNA fragment<br />
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[[3kc4]] – EcRPS5 in 30S ribosomal subunit - ''Escherichia coli''<br />
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[[3i1m]], [[3i1o]], [[3df1]], [[3df3]], [[2vho]], [[2vhp]], [[2avy]], [[2aw7]], [[1pnx]] - EcRPS5 in 30S ribosomal subunit+16S RRNA<br />
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[[1i94]], [[1fka]] - TtRPS5 in 30S ribosomal subunit+16S RRNA<br />
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[[1p87]], [[1p6g]] - EcRPS5 in 30S ribosomal subunit+16S RRNA – Cryo-EM<br />
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[[3bbn]] - RPS5 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach
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===S8 in small + large ribosomal subunit===
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[[1ml5]] - EcRPS5 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM
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===S8 in small ribosomal subunit+ chain release factor===
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[[3mr8]], [[3ms0]] – TtRPS5 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA <br />
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[[3d5a]], [[3d5c]] - TtRPS5 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
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[[2b64]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1<br />
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[[2b9m]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2<br />
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[[2x9r]], [[2x9t]], [[2wh1]], [[2wh3]] - TtRPS5 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA<br />
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[[3f1e]], [[3f1g]] - TtRPS5 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA
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===S8 in small ribosomal subunit+tRNA+mRNA===
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[[2hgi]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet<br />
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[[2hgp]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
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[[2i2p]], [[2i2u]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
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[[2hgr]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA<br />
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[[1yl4]] – TtRPS5 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator<br />
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[[1pns]] - EcRPS5 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA <br />
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[[1xnq]], [[1xnr]] - TtRPS5 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA
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===S8 in small ribosomal subunit+A-site tRNA===
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[[2uxd]], [[2uxc]] - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA<br />
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[[1n32]], [[1n33]] - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA<br />
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[[1n34]] - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA<br />
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[[1xmo]], [[1xmq]] - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA<br />
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[[2uxb]] - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA
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===S8 in small ribosomal subunit+P-site tRNA===
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[[3i8g]] - TtRPS5 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA<br />
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[[3i8h]], [[3i9b]], [[3i9d]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA<br />
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[[1ibk]] - TtRPS5 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA<br />
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[[2wwl]] - EcRPS5 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - ''Escherichia coli''<br />
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[[3i1q]] - EcRPS5 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA<br />
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[[3i1s]], [[3i1z]], [[3i21]] - EcRPS5 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA
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===S8 in small ribosomal subunit+A-site tRNA+P-site tRNA===
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[[1ibl]], [[1ibm]] - TtRPS5 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA
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===S8 in small ribosomal subunit+P-site tRNA+E-site tRNA===
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[[2ow8]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA<br />
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[[2b9o]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA<br />
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[[2qnh]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
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[[2wdg]], [[2wdh]], [[2wdk]], [[2wdm]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe
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===S8 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA===
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[[2gy9]], [[2gyb]] - EcRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM<br />
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[[1jgo]], [[1jgp]], [[1jgq]], [[1gix]] - TtRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA<br />
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[[3e1a]], [[3e1c]] - EcRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA
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===S8 in small ribosomal subunit + antibiotics===
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[[1i95]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+edeine<br />
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[[1i97]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+tetracycline<br />
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[[1hnw]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+tetracycline<br />
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[[1hnx]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+pactamycin <br />
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[[1hnz]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+hygromycin B<br />
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[[1fjg]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+mRNA fragment+streptomycin<br />
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[[2qbb]], [[2qb9]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+kasugamyin<br />
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[[2hhh]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+kasugamyin<br />
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[[2f4v]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+designed antibiotic<br />
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[[1vs5]], [[1vs7]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+gentamicin<br />
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[[2qan]], [[2qal]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+neomycin<br />
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[[2qou]], [[2qow]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+spectinomycin<br />
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[[2qoy]], [[2qp0]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+spectinomycin+neomycin<br />
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[[2z4k]], [[2z4m]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+paromomycin<br />
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[[2j00]], [[2j02]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA<br />
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[[3knj]], [[3knh]] - TtRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin<br />
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[[3knl]], [[3knn]] - TtRPS5 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin
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===S8 in small ribosomal subunit + ribosome recycling factor===
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[[2qbd]], [[2qbf]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor<br />
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[[2qbh]], [[2qbj]] - EcRPS5 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin<br />
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[[2v46]], [[2v48]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet
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===S8 in small ribosomal subunit + elongation factor===
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[[2wri]], [[2wrk]] - TtRPS5 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G<br />
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[[2wrn]], [[2wrq]] - TtRPS5 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4<br />
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[[3fic]] - TtRPS5 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A<br />
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[[3fih]] - EcRPS5 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU<br />
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[[3huw]], [[3huy]] - TtRPS5 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P<br />
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===S8 in small ribosomal subunit + translation initiation factor===
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[[1i96]] - TtRPS5 in 30S ribosomal subunit+THX+IF3+16S RRNA<br />
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[[1hr0]] - TtRPS5 in 30S ribosomal subunit+THX+IF+16S RRNA
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===S8 in small ribosomal subunit + various proteins===
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[[3kiq]], [[3kis]], [[3kiu]], [[3kix]] - TtRPS5 in 30S ribosomal subunit+toxin RelE+16S RRNA<br />
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*Ribosomal protein S8
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[[1voq]], [[1vos]], [[1vov]], [[1vox]], [[1voz]] - EcRPS5 in 30S ribosomal subunit+protein Y+16S RRNA<br />
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===S8 in part of small ribosomal subunit===
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**[[1an7]] – TtRPS8 - ''Thermus thermophilus''<br />
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**[[1sei]] – RPS8 – ''Geobacillus stearothermophilus''<br />
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**[[3rf2]] – RPS8 – ''Aquifex aeolicus''<br />
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**[[2kcp]], [[2kcy]] – RPS8E – ''Methanothermobacter thermaututrophicus'' – NMR<br />
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**[[2kco]] – RPS8E – ''Sulfolobus solfataricus'' - NMR<br />
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**[[4pdb]] – RPS8 + RNA – ''Bacillus anthracis''<br />
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[[1qd7]] – TtRPS5+TtRPS4+TtRPS6+TtRPS7+TtRPS8+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
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*Ribosomal protein S8 in part of small ribosomal subunit
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[[3iy8]] - EcRPS8+EcRPS5+EcRPS6+EcRPS9+EcRPS9 EcRPS11+EcRPS12+EcRPS15+EcRPS16+EcRPS17+EcRPS18+''Leishmania taretolae'' mRNA<br />
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[[1s03]] - EcRPS8+spc operon mRNA<br />
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[[1i6u]] - RPS8+16S RRNA fragment – ''Methanococcus jannaschii''<br />
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[[1emi]] - TtRPS8+16S RRNA
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**[[1qd7]] – TtRPS8+TtRPS4+TtRPS6+TtRPS7+TtRPS5+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
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**[[3iy8]] - EcRPS8+EcRPS5+EcRPS6+EcRPS9+ EcRPS11+EcRPS12+EcRPS15+EcRPS16+EcRPS17+EcRPS18+''Leishmania taretolae'' mRNA <br />
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**[[1s03]] - EcRPS8+spc operon mRNA<br />
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**[[1i6u]] - RPS8+16S RRNA fragment – ''Methanococcus jannaschii''<br />
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**[[1emi]] - TtRPS8+16S RRNA
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}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Ribosomal protein S8 (PDB code 1sei)

Drag the structure with the mouse to rotate

3D Structures of Ribosomal protein S8

Updated on 01-October-2017

References

  1. Wower I, Kowaleski MP, Sears LE, Zimmermann RA. Mutagenesis of ribosomal protein S8 from Escherichia coli: defects in regulation of the spc operon. J Bacteriol. 1992 Feb;174(4):1213-21. PMID:1735715

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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