Ribosomal protein S8

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[[Image:RPS8.png|left|200px|thumb|Crystal Structure of Ribosomal protein S8 from [[2zm6]], chain H]]
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<StructureSection load='1sei' size='350' side='right' scene='' caption='Ribosomal protein S8 (PDB code [[1sei]])'>
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{{STRUCTURE_1sei| PDB=1sei | SIZE=400| SCENE=|right|CAPTION=Ribosomal protein S8 dimer from [[1sei]] }}
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[[Ribosomal protein S8]] (RPS8) is one of the 21 proteins which belong to the 30S <scene name='Ribosomal_protein_S8/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]] or the 30 proteins which belong to the 40S small subunit of the eukaryotic ribosome. It binds to 16S RRNA and interacts with spc operon mRNA<ref>PMID:1735715</ref>. In archaea the protein is named S8E (RPS8E).
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</StructureSection>
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[[Ribosomal protein S8]] (RPS8) is one of the 22 proteins which belong to the <scene name='Ribosomal_protein_S8/Cv/2'>small subunit</scene> of the [http://en.wikipedia.org/wiki/Bacteria bacterial] [[ribosome]]. It binds to 16S RRNA and interacts with spc operon mRNA. In archaea the protein is named S8E (RPS8E). The images at the left and at the right correspond to one representative RPS8, ''i.e.'' the crystal structure of Ribosomal protein S8 from ''Thermus thermophilus'' ([[2zm6]], chain H).
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{{TOC limit|limit=2}}
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== 3D Structures of Ribosomal protein S8 ==
== 3D Structures of Ribosomal protein S8 ==
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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{{#tree:id=OrganizedByTopic|openlevels=0|
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===RPS8===
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*Ribosomal protein S8
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[[1an7]] – TtRPS8 - ''Thermus thermophilus''<br />
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[[1sei]] – RPS8 – ''Geobacillus stearothermophilus''<br />
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[[3rf2]] – RPS8 – ''Aquifex aeolicus''<br />
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[[2kcp]], [[2kcy]] – RPS8E – ''Methanothermobacter thermaututrophicus'' – NMR<br />
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[[2kco]] – RPS8E – ''Sulfolobus solfataricus'' - NMR
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===S8 in small ribosomal subunit===
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[[2zm6]], [[1n36]], [[1j5e]], [[3oge]], [[3ogy]], [[3ohc]], [[3ohd]], [[3ohy]], [[3oi0]], [[3oi2]], [[3oi4]], [[3oto]] - TtRPS8 in 30S ribosomal subunit+THX+16S RRNA – ''Thermus thermophilus''<br />
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[[2vqe]], [[2vqf]], [[2uuc]], [[2e5l]], [[2uu9]], [[2uua]], [[2uub]], [[3pyn]], [[3pyq]], [[3pys]], [[3pyu]] - TtRPS5 in 30S ribosomal subunit+16S RRNA+RNA fragment<br />
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[[3kc4]] – EcRPS8 in 30S ribosomal subunit - ''Escherichia coli''<br />
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[[3i1m]], [[3i1o]], [[3df1]], [[3df3]], [[2vho]], [[2vhp]], [[2avy]], [[2aw7]], [[1pnx]], [[3oaq]], [[3oar]], [[3ofa]], [[3ofb]], [[3ofo]], [[3ofp]], [[3ofx]], [[3ofy]], [[3or9]], [[3ora]] - EcRPS8 in 30S ribosomal subunit+16S RRNA<br />
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[[1i94]], [[1fka]], [[3uxs]], [[3uxt]], [[4dr1]] - TtRPS8 in 30S ribosomal subunit+16S RRNA<br />
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[[4dr4]] – TtRPS8 in 30S ribosomal subunit+16S RRNA + mRNA<br />
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[[1p87]], [[1p6g]] - EcRPS8 in 30S ribosomal subunit+16S RRNA – Cryo-EM<br />
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[[3bbn]] - RPS8 in 30S ribosomal subunit+16S RRNA – Cryo-EM – spinach
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===S8 in small + large ribosomal subunit===
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[[1ml5]] - EcRPS8 in 30S ribosomal subunit+50S ribosomal subunit+THX+chain release factor 2+P-site tRNA+tRNA Phe+mRNA fragment+23S RRNA+5S RRNA+16S RRNA - EM
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===S8 in small ribosomal subunit+ chain release factor===
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[[3mr8]], [[3ms0]] – TtRPS8 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+mRNA+16S RRNA <br />
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[[3d5a]], [[3d5c]] - TtRPS8 in 30S ribosomal subunit+THX+chain release factor 1+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
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[[3zvo]] – TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA Met +mRNA +16S RRNA+chain release factor 3<br />
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[[2b64]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 1<br />
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[[2b9m]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA+chain release factor 2<br />
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[[2x9r]], [[2x9t]], [[2wh1]], [[2wh3]] - TtRPS8 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+mRNA +16S RRNA<br />
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[[3f1e]], [[3f1g]] - TtRPS8 in 30S ribosomal subunit+THX+chain release factor 2+P-site tRNA+E-site tRNA +16S RRNA<br />
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[[3uoq]] - EcRPS8 + 16S RRNA + mRNA + peptide chain release factor<br />
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===S8 in small ribosomal subunit+tRNA+mRNA===
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[[2hgi]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet<br />
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[[2hgp]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
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[[3t1h]], [[3t1y]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Lys +mRNA<br />
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[[3tvf]], [[3tvg]], [[3uyd]], [[3uyf]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Leu + tRNA fMet + mRNA<br />
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[[3uz6]], [[3uz7]], [[3uzg]], [[3uzi]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Tyr + tRNA fMet + mRNA<br />
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[[2i2p]], [[2i2u]] - EcRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Phe+mRNA<br />
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[[2hgr]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Phe+tRNA fMet+mRNA<br />
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[[1yl4]] – TtRPS8 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+THRS mRNA operator<br />
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[[1pns]] - EcRPS8 in 30S ribosomal subunit+ tRNA Phe+16S RRNA+mRNA <br />
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[[3j0u]], [[3j0v]], [[3j0x]], [[3j0z]], [[3j10]], [[3j20]] – EcRPS8 in 30S ribosomal subunit+ A-site tRNA + P-site tRNA +16S RRNA+mRNA – Cryo-EM<br />
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[[3j13]] – EcRPS8 in 30S ribosomal subunit+ P-site tRNA +16S RRNA+mRNA – Cryo-EM<br />
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[[1xnq]], [[1xnr]] - TtRPS8 in 30S ribosomal subunit+THX+mRNA+tRNA anticodon+16S RRNA
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===S8 in small ribosomal subunit+A-site tRNA===
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[[2uxd]], [[2uxc]] - TtRPS8 in 30S ribosomal subunit+THX+A-site mRNA CGGG+tRNA anticodon+16S RRNA<br />
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[[1n32]], [[1n33]] - TtRPS8 in 30S ribosomal subunit+THX+A-site mRNA fragment+tRNA anticodon+16S RRNA<br />
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[[1n34]] - TtRPS8 in 30S ribosomal subunit+THX+A-site mRNA fragment +16S RRNA<br />
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[[1xmo]], [[1xmq]] - TtRPS8 in 30S ribosomal subunit+THX+A-site mRNA+tRNA anticodon+16S RRNA<br />
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[[2uxb]] - TtRPS8 in 30S ribosomal subunit+THX+A-site mRNA GGGU+tRNA anticodon+16S RRNA
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===S8 in small ribosomal subunit+P-site tRNA===
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[[3i8g]] - TtRPS8 in 30S ribosomal subunit+P-site tRNA+mRNA +16S RRNA<br />
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[[3i8h]], [[3i9b]], [[3i9d]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA<br />
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[[1ibk]] - TtRPS8 in 30S ribosomal subunit+THX+P-site mRNA fragment +16S RRNA<br />
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[[2wwl]] - EcRPS8 in 30S ribosomal subunit+Poly-Ala chain+P-site tRNA+mRNA +16S RRNA - ''Escherichia coli''<br />
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[[3i1q]] - EcRPS8 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA<br />
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[[3i1s]], [[3i1z]], [[3i21]] - EcRPS8 in 30S ribosomal subunit+P-site tRNA hairpin+mRNA +16S RNA
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===S8 in small ribosomal subunit+A-site tRNA+P-site tRNA===
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[[1ibl]], [[1ibm]] - TtRPS8 in 30S ribosomal subunit+THX+A-site mRNA fragment+P-site mRNA fragment+tRNA anticodon+16S RRNA
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===S8 in small ribosomal subunit+P-site tRNA+E-site tRNA===
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[[2ow8]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA+mRNA +16S RRNA<br />
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[[2b9o]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA Phe+E-site tRNA Phe+mRNA +16S RRNA<br />
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[[2qnh]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA<br />
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[[2wdg]], [[2wdh]], [[2wdk]], [[2wdm]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA+E-site tRNA+mRNA +16S RRNA+tRNA Phe
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===S8 in small ribosomal subunit+A-site tRNA+P-site tRNA+E-site tRNA===
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[[2gy9]], [[2gyb]] - EcRPS8 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA – Cryo-EM<br />
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[[1jgo]], [[1jgp]], [[1jgq]], [[1gix]] - TtRPS8 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+tRNA Phe+mRNA +16S RRNA<br />
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[[3e1a]], [[3e1c]] - EcRPS8 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA
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===S8 in small ribosomal subunit + antibiotics===
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[[1i95]], [[1i97]], [[2hhh]], [[2f4v]], [[4dr2]], [[4dr3]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+antibiotic<br />
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[[1hnw]], [[1hnx]], [[1hnz]], [[1fjg]], [[4aqy]], [[4dr5]], [[4dr6]], [[4dr7]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+mRNA fragment+antibiotic<br />
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[[2qbb]], [[2qb9]], [[1vs5]], [[1vs7]], [[2qan]], [[2qal]], [[2qou]], [[2qow]], [[2qoy]], [[2qp0]], [[2z4k]], [[2z4m]] - EcRPS8 in 30S ribosomal subunit+16S RRNA+antibiotic<br />
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[[3sfs]] – EcRPS8 in 30S ribosomal subunit+16S RRNA+ mRNA + RF-3 + antibiotic<br />
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[[4gaq]], [[4gas]] – EcRPS8 in 30S ribosomal subunit+16S RRNA+ mRNA + antibiotic<br />
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[[2j00]], [[2j02]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+paromomycin+P-site tRNA fMet+E-site tRNA Phe+mRNA<br />
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[[3knj]], [[3knh]] - TtRPS8 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+viomycin<br />
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[[3knl]], [[3knn]] - TtRPS8 in 30S ribosomal subunit+P-site tRNA+A-site tRNA+E-site tRNA+mRNA +16S RRNA+capreomycin<br />
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[[3uz3]], [[3uz4]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Leu + tRNA fMet + mRNA + paromomycin<br />
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[[3uzl]], [[3uzm]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+tRNA Tyr + tRNA fMet + mRNA + paromomycin
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===S8 in small ribosomal subunit + ribosome recycling factor===
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[[2qbd]], [[2qbf]] - EcRPS8 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor<br />
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[[3r8n]], [[3r8o]], [[4gd1]], [[4gd2]] – EcRPS7 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor + mRNA + tRNA<br />
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[[2qbh]], [[2qbj]] - EcRPS8 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+gentamicin<br />
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[[2v46]], [[2v48]] - TtRPS8 in 30S ribosomal subunit+16S RRNA+ribosome recycling factor+P-site tRNA Phe+mRNA+tRNA fMet
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===S8 in small ribosomal subunit + elongation factor===
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[[2wri]], [[2wrk]], [[2xsy]], [[2xuy]] - TtRPS8 in 30S ribosomal subunit+THX+P-site tRNA+mRNA +16S RRNA+elongation factor G<br />
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[[2wrn]], [[2wrq]] - TtRPS8 in 30S ribosomal subunit+THX+A-site tRNA+mRNA +16S RRNA+elongation factor TU-4<br />
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[[3fic]] - TtRPS8 in 30S ribosomal subunit+THX+A-site tRNA+P-site tRNA+E-site tRNA+mRNA codon+16S RRNA+elongation factor TU-A<br />
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[[4abr]] - TtRPS8 in 30S ribosomal subunit+THX + E/P-site tRNA fMet +mRNA codon+16S RRNA+elongation factor TU<br />
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[[3izv]] – EcRPS8 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+elongation factor TU<br />
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[[3j18]] - EcRPS8 in 30S ribosomal subunit+A/T-site tRNA Phe +16S RRNA+ mRNA + SSRA-binding protein + formyl-Met specific initiator tRNA + elongation factor G – Cryo-EM<br />
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[[3izw]] – EcRPS8 in 30S ribosomal subunit+A-site tRNA Phe +mRNA +16S RRNA+elongation factor TU<br />
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[[2y0u]], [[2y0w]], [[2y0y]], [[2y10]], [[2y12]], [[2y14]], [[2y16]], [[2y18]] - TtRPS8 in 30S subunit+THX+A-site tRNA+E-site tRNA+mRNA codon+16S RRNA + elongation factor TU<br />
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[[3fih]] - EcRPS8 in 30S ribosomal subunit+A-site tRNA Phe+P-site tRNA+mRNA +16S RRNA+elongation factor TU<br />
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[[3huw]], [[3huy]] - TtRPS8 in 30S ribosomal subunit+THX+tRNA-Met+mRNA +16S RRNA+elongation factor P<br />
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[[2xqd]] - TtRPS8 in 30S ribosomal subunit+THX+E-site tRNA+mRNA +16S RRNA+elongation factor TU-B<br />
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===S8 in small ribosomal subunit + translation initiation factor===
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[[1i96]] - TtRPS8 in 30S ribosomal subunit+THX+IF3+16S RRNA<br />
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[[1hr0]] - TtRPS8 in 30S ribosomal subunit+THX+IF+16S RRNA
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===S8 in small ribosomal subunit + various proteins===
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[[3kiq]], [[3kis]], [[3kiu]], [[3kix]] - TtRPS8 in 30S ribosomal subunit+toxin RelE+16S RRNA<br />
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[[1voq]], [[1vos]], [[1vov]], [[1vox]], [[1voz]] - EcRPS8 in 30S ribosomal subunit+protein Y+16S RRNA<br />
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[[2xzm]], [[2xzn]] - RPS8 in 40S subunit+18S RRNA+RACK1 - ''Tetrahymena thermophila''<br />
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[[2xfz]], [[2xg1]] - TtRPS8 in 30S ribosomal subunit+colicin E3+E-site tRNA+mRNA+16S RRNA<br />
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[[4dh9]], [[4dhb]] - TtRPS8 in 30S ribosomal subunit +16S RRNA+mRNA+P-site tRNA fMet +THX + YAEJ<br />
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[[3j00]] – EcRPS8 + 16S RRNA + FTSQ + apolipoprotein A-I<br />
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[[2ykr]] – EcRPS8 + 16S RRNA + GMPPNP + GTPase RSGA<br />
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[[4a2i]] – EcRPS8 + 16S RRNA + GTPase RSGA – Cryo EM<br />
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[[4adv]] - EcRPS8 + 16S RRNA + methyltransferase – Cryo EM<br />
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[[3v22]], [[3v24]], [[3v26]], [[3v28]] – TtRPS8 in 30S ribosomal subunit +16S RRNA +THX + modulation factor<br />
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[[3v2c]], [[3v2e]] – TtRPS8 in 30S ribosomal subunit +16S RRNA +THX + ribosome-associated inhibitor<br />
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[[3iz6]] - RPS8 in 40S ribosomal subunit+RACK1 – wheat – Cryo EM <br />
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[[3izb]] - yRPS8 in 40S ribosomal subunit+ RACK1 – yeast - Cryo-EM<br />
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[[3u5c]], [[3u5g]] - yRPS8 in 40S ribosomal subunit+ RACK1 + suppressor protein SMT1<br />
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===S8 in part of small ribosomal subunit===
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**[[1an7]] – TtRPS8 - ''Thermus thermophilus''<br />
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**[[1sei]] – RPS8 – ''Geobacillus stearothermophilus''<br />
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**[[3rf2]] – RPS8 – ''Aquifex aeolicus''<br />
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**[[2kcp]], [[2kcy]] – RPS8E – ''Methanothermobacter thermaututrophicus'' – NMR<br />
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**[[2kco]] – RPS8E – ''Sulfolobus solfataricus'' - NMR<br />
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**[[4pdb]] – RPS8 + RNA – ''Bacillus anthracis''<br />
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[[1qd7]] – TtRPS8+TtRPS4+TtRPS6+TtRPS7+TtRPS5+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
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*Ribosomal protein S8 in part of small ribosomal subunit
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[[3iy8]] - EcRPS8+EcRPS5+EcRPS6+EcRPS9+EcRPS9 EcRPS11+EcRPS12+EcRPS15+EcRPS16+EcRPS17+EcRPS18+''Leishmania taretolae'' mRNA<br />
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[[1s03]] - EcRPS8+spc operon mRNA<br />
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[[1i6u]] - RPS8+16S RRNA fragment – ''Methanococcus jannaschii''<br />
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[[1emi]] - TtRPS8+16S RRNA
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**[[1qd7]] – TtRPS8+TtRPS4+TtRPS6+TtRPS7+TtRPS5+TtRPS15+TtRPS17+TtRPS20+16S RRNA fragment<br />
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**[[3iy8]] - EcRPS8+EcRPS5+EcRPS6+EcRPS9+ EcRPS11+EcRPS12+EcRPS15+EcRPS16+EcRPS17+EcRPS18+''Leishmania taretolae'' mRNA <br />
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**[[1s03]] - EcRPS8+spc operon mRNA<br />
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**[[1i6u]] - RPS8+16S RRNA fragment – ''Methanococcus jannaschii''<br />
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**[[1emi]] - TtRPS8+16S RRNA
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}}
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== References ==
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<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Ribosomal protein S8 (PDB code 1sei)

Drag the structure with the mouse to rotate

3D Structures of Ribosomal protein S8

Updated on 01-October-2017

References

  1. ↑ Wower I, Kowaleski MP, Sears LE, Zimmermann RA. Mutagenesis of ribosomal protein S8 from Escherichia coli: defects in regulation of the spc operon. J Bacteriol. 1992 Feb;174(4):1213-21. PMID:1735715

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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