Thiol peroxidase
From Proteopedia
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| - | {{STRUCTURE_3hvs| PDB=3hvs | SIZE=400| SCENE= |right|CAPTION=E. coli thiol peroxidase dimer complex with citric acid, [[3hvs]] }} | ||
| - | ''' | + | <StructureSection load='3hvs' size='350' side='right' scene='' caption='E. coli thiol peroxidase dimer complex with citric acid (PDB code [[3hvs]])'> |
| + | '''Thiol peroxidase''' (TPX) is part of an oxidative stress defense system that uses thioredoxin and thioredoxin reductase to reduce alkyl hydroperoxides. TPX is an antioxidant which reduces peroxides and inhibits hydrogen peroxide response. TPX is also implicated in activation of transcription factors and signaling<ref>PMID:20649470</ref>. | ||
| + | </StructureSection> | ||
==3D structures of thiol peroxidase== | ==3D structures of thiol peroxidase== | ||
Revision as of 22:46, 6 October 2017
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3D structures of thiol peroxidase
Updated on 06-October-2017
1q98 – TPX – Haemophilus influenzae
1qxh, 3hvs, 3i43, 4af2 – EcTPX – Escherichia coli
3hvv, 3hvx - EcTPX (mutant)
1xvq – TPX – Mycobacterium tuberculosis
2xpd, 2xpe, 3zrd, 3zre – YpTPX – Yersinia pseudotuberculosis
2yjh - YpTPX (mutant)
4gqc, 4gqf – TPX – Aeropyrum pernix
References
- ↑ Flohe L, Toppo S, Cozza G, Ursini F. A comparison of thiol peroxidase mechanisms. Antioxid Redox Signal. 2011 Aug 1;15(3):763-80. doi: 10.1089/ars.2010.3397. Epub , 2010 Nov 1. PMID:20649470 doi:http://dx.doi.org/10.1089/ars.2010.3397
