TRNA-guanine transglycosylase

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**[[2z7k]], [[3rr4]], [[3tll]], [[4fr6]], [[4fsa]], [[4fr1]], [[4fps]], [[4gi4]], [[4giy]], [[4gkt]], [[4kwo]], [[4lbu]], [[4leq]], [[5i09]] – ZmTGT + benzoguanine derivative<BR />
**[[2z7k]], [[3rr4]], [[3tll]], [[4fr6]], [[4fsa]], [[4fr1]], [[4fps]], [[4gi4]], [[4giy]], [[4gkt]], [[4kwo]], [[4lbu]], [[4leq]], [[5i09]] – ZmTGT + benzoguanine derivative<BR />
**[[5j9m]], [[5j9n]], [[5j9o]], [[5jt5]], [[5jt6]], [[5jt7]] – ZmTGT + benzoimidazole derivative<BR />
**[[5j9m]], [[5j9n]], [[5j9o]], [[5jt5]], [[5jt6]], [[5jt7]] – ZmTGT + benzoimidazole derivative<BR />
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**[[4q4r]], [[3s1g]], [[3sm0]], [[4gg9]], [[4gh1]], [[4gh3]], [[4ghr]] – ZmTGT + benzohypoxanthine derivative<BR />
+
**[[3s1g]], [[3sm0]], [[4gg9]], [[4gh1]], [[4gh3]], [[4ghr]] – ZmTGT + benzohypoxanthine derivative<BR />
*Archaebacterial tRNA-guanine transglycosylase
*Archaebacterial tRNA-guanine transglycosylase

Revision as of 19:57, 28 December 2017

Structure of tRNA-guanine transglycosylase complex with queuine precursor and Zn+2 ion (grey) (PDB entry 1p0e)

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3D structures of tRNA-guanine transglycosylase

Updated on 28-December-2017

References

  1. Nonekowski ST, Garcia GA. tRNA recognition by tRNA-guanine transglycosylase from Escherichia coli: the role of U33 in U-G-U sequence recognition. RNA. 2001 Oct;7(10):1432-41. PMID:11680848
  2. Sabina J, Soll D. The RNA-binding PUA domain of archaeal tRNA-guanine transglycosylase is not required for archaeosine formation. J Biol Chem. 2006 Mar 17;281(11):6993-7001. Epub 2006 Jan 10. PMID:16407303 doi:http://dx.doi.org/M512841200
  3. Brenk R, Stubbs MT, Heine A, Reuter K, Klebe G. Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design. Chembiochem. 2003 Oct 6;4(10):1066-77. PMID:14523925 doi:10.1002/cbic.200300644

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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