Thioredoxin Reductase

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Line 23: Line 23:
**[[3r9u]] – TrxR – ''Campylobacter jejuni''<br />
**[[3r9u]] – TrxR – ''Campylobacter jejuni''<br />
**[[4zn0]] – TrxR – ''Methanosarcina mazei''<br />
**[[4zn0]] – TrxR – ''Methanosarcina mazei''<br />
-
**[[4xrd]], [[4xs1]], [[4xs4]], [[4xs6]], [[4xs8]], [[4xts]], [[4xra]] – TrxR (mutant) – ''Salmonella enterica''<br />
+
**[[4xrd]], [[4xs1]], [[4xs4]], [[4xs6]], [[5uka]], [[4xts]], [[4xra]] – TrxR (mutant) – ''Salmonella enterica''<br />
*Thioredoxin reductase complex with FAD
*Thioredoxin reductase complex with FAD

Revision as of 09:40, 19 February 2018

Human Thioredoxin reductase dimer (cyan, green) complex with thioredoxin (yellow, pink), glycerol and FAD (PDB entry 3qfa)

Drag the structure with the mouse to rotate

3D Structures of Thioredoxin Reductase

Updated on 19-February-2018

References

  1. Arner ES, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem. 2000 Oct;267(20):6102-9. PMID:11012661
  2. Prasad R, Chan LF, Hughes CR, Kaski JP, Kowalczyk JC, Savage MO, Peters CJ, Nathwani N, Clark AJ, Storr HL, Metherell LA. Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD). J Clin Endocrinol Metab. 2014 Aug;99(8):E1556-63. doi: 10.1210/jc.2013-3844. Epub, 2014 Mar 6. PMID:24601690 doi:http://dx.doi.org/10.1210/jc.2013-3844
  3. Fritz-Wolf K, Kehr S, Stumpf M, Rahlfs S, Becker K. Crystal structure of the human thioredoxin reductase-thioredoxin complex. Nat Commun. 2011 Jul 12;2:383. doi: 10.1038/ncomms1382. PMID:21750537 doi:10.1038/ncomms1382

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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