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2z2c

From Proteopedia

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[[Image:2z2c.png|left|200px]]
 
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==MURA inhibited by unag-cnicin adduct==
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The line below this paragraph, containing "STRUCTURE_2z2c", creates the "Structure Box" on the page.
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<StructureSection load='2z2c' size='340' side='right'caption='[[2z2c]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2z2c]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Z2C FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.05&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=IAS:BETA-L-ASPARTIC+ACID'>IAS</scene>, <scene name='pdbligand=UDC:2-(ACETYLAMINO)-3-O-[(2S,3S)-2-CARBOXY-3,4-DIHYDROXYBUTAN-2-YL]-2-DEOXY-ALPHA-D-GLUCOPYRANOSE'>UDC</scene>, <scene name='pdbligand=UDP:URIDINE-5-DIPHOSPHATE'>UDP</scene></td></tr>
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{{STRUCTURE_2z2c| PDB=2z2c | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2z2c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2z2c OCA], [https://pdbe.org/2z2c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2z2c RCSB], [https://www.ebi.ac.uk/pdbsum/2z2c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2z2c ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MURA_ECOLI MURA_ECOLI] Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine. Target for the antibiotic phosphomycin.[HAMAP-Rule:MF_00111]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/z2/2z2c_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2z2c ConSurf].
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<div style="clear:both"></div>
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===MURA inhibited by unag-cnicin adduct===
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==See Also==
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*[[Enoylpyruvate transferase 3D structures|Enoylpyruvate transferase 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_018672863}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 018672863 is the PubMed ID number.
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{{ABSTRACT_PUBMED_018672863}}
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==About this Structure==
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[[2z2c]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Z2C OCA].
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==Reference==
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<ref group="xtra">PMID:018672863</ref><references group="xtra"/>
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: UDP-N-acetylglucosamine 1-carboxyvinyltransferase]]
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[[Category: Large Structures]]
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[[Category: Klein, C D.]]
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[[Category: Klein CD]]
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[[Category: Scheidig, A J.]]
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[[Category: Scheidig AJ]]
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[[Category: Skarzynski, T.]]
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[[Category: Skarzynski T]]
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[[Category: Steinbach, A.]]
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[[Category: Steinbach A]]
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[[Category: Cnicin]]
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[[Category: Peptidoglycan]]
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[[Category: Transferase]]
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[[Category: Transferase-transferase inhibitor complex]]
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[[Category: Udp-n-acetylglucosamine]]
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Current revision

MURA inhibited by unag-cnicin adduct

PDB ID 2z2c

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