Thiol peroxidase

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{{STRUCTURE_3hvs| PDB=3hvs | SIZE=400| SCENE= |right|CAPTION=E. coli thiol peroxidase complex with citric acid, [[3hvs]] }}
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<StructureSection load='3hvs' size='350' side='right' scene='' caption='E. coli thiol peroxidase dimer complex with citric acid (PDB code [[3hvs]])'>
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'''Thiol peroxidase''' (TPX) is part of an oxidative stress defense system that uses thioredoxin and thioredoxin reductase to reduce alkyl hydroperoxides. TPX is an antioxidant which reduces peroxides and inhibits hydrogen peroxide response. TPX is also implicated in activation of transcription factors and signaling<ref>PMID:20649470</ref>. See also [[Bacterioferritin comigratory protein]].
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For yeast thiol peroxidase see [[Peroxiredoxin]]
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'''Thiol peroxidase''' (TPX) is part of an oxidative stress defense system that uses thioredoxin and thioredoxin reductase to reduce alkyl hydroperoxides. TPX is an antioxidant which reduces peroxides and inhibits hydrogen peroxide response. TPX is also implicated in activation of transcription factors and signaling.
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==3D structures of thiol peroxidase==
==3D structures of thiol peroxidase==
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[[1q98]] – TPX – ''Haemophilus influenzae''<br />
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[[Thiol peroxidase 3D structures]]
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[[1qxh]], [[3hvs]], [[3i43]] – EcTPX – ''Escherichia coli''<br />
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[[3hvv]], [[3hvx]] - EcTPX (mutant)<br />
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== References ==
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[[1xvq]] – TPX – ''Mycobacterium tuberculosis''<br />
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<references/>
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[[2a4v]] – TPX C terminal (mutant) – yeast<br />
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</StructureSection>
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[[2xpd]], [[2xpe]], [[3zrd]], [[3zre]] – YpTPX – ''Yersinia pseudotuberculosis''<br />
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[[Category: Topic Page]]
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[[2yjh]] - YpTPX (mutant)
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Current revision

E. coli thiol peroxidase dimer complex with citric acid (PDB code 3hvs)

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Michal Harel, Joel L. Sussman, Alexander Berchansky

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