1vka

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[[Image:1vka.jpg|left|200px]]<br /><applet load="1vka" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1vka, resolution 1.60&Aring;" />
 
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'''Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment'''<br />
 
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==About this Structure==
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==Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment==
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1VKA is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VKA OCA].
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<StructureSection load='1vka' size='340' side='right'caption='[[1vka]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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[[Category: Homo sapiens]]
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== Structural highlights ==
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[[Category: Single protein]]
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<table><tr><td colspan='2'>[[1vka]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VKA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VKA FirstGlance]. <br>
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[[Category: Dailey, H.A.]]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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[[Category: Dailey, T.A.]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vka FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vka OCA], [https://pdbe.org/1vka PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vka RCSB], [https://www.ebi.ac.uk/pdbsum/1vka PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vka ProSAT], [https://www.topsan.org/Proteins/SECSG/1vka TOPSAN]</span></td></tr>
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[[Category: Liu, Z.J.]]
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</table>
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[[Category: Mayer, M.R.]]
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== Function ==
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[[Category: Rose, J.P.]]
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[https://www.uniprot.org/uniprot/MARE1_HUMAN MARE1_HUMAN] Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes cytoplasmic microtubule nucleation and elongation. May be involved in spindle function by stabilizing microtubules and anchoring them at centrosomes. May play a role in cell migration.<ref>PMID:12388762</ref> <ref>PMID:21646404</ref> <ref>PMID:16109370</ref> <ref>PMID:19632184</ref>
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[[Category: SECSG, Southeast.Collaboratory.for.Structural.Genomics.]]
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== Evolutionary Conservation ==
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[[Category: Schubot, F.D.]]
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[[Image:Consurf_key_small.gif|200px|right]]
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[[Category: Shah, A.]]
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Check<jmol>
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[[Category: Tempel, W.]]
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<jmolCheckbox>
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[[Category: Wang, B.C.]]
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/vk/1vka_consurf.spt"</scriptWhenChecked>
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[[Category: homo sapiens]]
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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[[Category: protein structure initiative]]
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<text>to colour the structure by Evolutionary Conservation</text>
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[[Category: psi]]
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</jmolCheckbox>
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[[Category: q15691]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1vka ConSurf].
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[[Category: secsg]]
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<div style="clear:both"></div>
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[[Category: southeast collaboratory for structural genomics]]
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[[Category: structural genomics]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Feb 15 17:05:02 2008''
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==See Also==
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*[[End-binding protein|End-binding protein]]
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*[[Microtubule-associated protein 3D structures|Microtubule-associated protein 3D structures]]
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Dailey HA]]
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[[Category: Dailey TA]]
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[[Category: Liu Z-J]]
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[[Category: Mayer MR]]
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[[Category: Rose JP]]
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[[Category: Schubot FD]]
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[[Category: Shah A]]
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[[Category: Tempel W]]
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[[Category: Wang B-C]]

Current revision

Southeast Collaboratory for Structural Genomics: Hypothetical Human Protein Q15691 N-Terminal Fragment

PDB ID 1vka

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