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1rxk

From Proteopedia

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{{Seed}}
 
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[[Image:1rxk.png|left|200px]]
 
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==crystal structure of streptavidin mutant (M3) a combination of M1+M2==
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The line below this paragraph, containing "STRUCTURE_1rxk", creates the "Structure Box" on the page.
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<StructureSection load='1rxk' size='340' side='right'caption='[[1rxk]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1rxk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RXK FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BNI:5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC+ACID+(4-NITRO-PHENYL)-AMIDE'>BNI</scene></td></tr>
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{{STRUCTURE_1rxk| PDB=1rxk | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rxk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rxk OCA], [https://pdbe.org/1rxk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rxk RCSB], [https://www.ebi.ac.uk/pdbsum/1rxk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rxk ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SAV_STRAV SAV_STRAV] The biological function of streptavidin is not known. Forms a strong non-covalent specific complex with biotin (one molecule of biotin per subunit of streptavidin).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rx/1rxk_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rxk ConSurf].
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<div style="clear:both"></div>
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===crystal structure of streptavidin mutant (M3) a combination of M1+M2===
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==See Also==
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*[[Avidin 3D structures|Avidin 3D structures]]
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__TOC__
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</StructureSection>
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The line below this paragraph, {{ABSTRACT_PUBMED_15079055}}, adds the Publication Abstract to the page
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[[Category: Large Structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 15079055 is the PubMed ID number.
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{{ABSTRACT_PUBMED_15079055}}
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==About this Structure==
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1RXK is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Streptomyces_avidinii Streptomyces avidinii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RXK OCA].
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==Reference==
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Structural elements responsible for conversion of streptavidin to a pseudoenzyme., Eisenberg-Domovich Y, Pazy Y, Nir O, Raboy B, Bayer EA, Wilchek M, Livnah O, Proc Natl Acad Sci U S A. 2004 Apr 20;101(16):5916-21. Epub 2004 Apr 12. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15079055 15079055]
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[[Category: Single protein]]
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[[Category: Streptomyces avidinii]]
[[Category: Streptomyces avidinii]]
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[[Category: Bayer, E A.]]
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[[Category: Bayer EA]]
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[[Category: Eisenberg-Domovich, Y.]]
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[[Category: Eisenberg-Domovich Y]]
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[[Category: Livnah, O.]]
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[[Category: Livnah O]]
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[[Category: Nir, O.]]
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[[Category: Nir O]]
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[[Category: Pazy, Y.]]
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[[Category: Pazy Y]]
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[[Category: Raboy, B.]]
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[[Category: Raboy B]]
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[[Category: Wilchek, M.]]
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[[Category: Wilchek M]]
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[[Category: Avidin]]
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[[Category: Pseudo enzymatic activity]]
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[[Category: Streptavidin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jul 28 17:11:49 2008''
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Current revision

crystal structure of streptavidin mutant (M3) a combination of M1+M2

PDB ID 1rxk

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