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3t06

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[[Image:3t06.jpg|left|200px]]
 
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==Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA==
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The line below this paragraph, containing "STRUCTURE_3t06", creates the "Structure Box" on the page.
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<StructureSection load='3t06' size='340' side='right'caption='[[3t06]], [[Resolution|resolution]] 2.84&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3t06]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T06 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3T06 FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.84&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3t06 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3t06 OCA], [https://pdbe.org/3t06 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3t06 RCSB], [https://www.ebi.ac.uk/pdbsum/3t06 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3t06 ProSAT]</span></td></tr>
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{{STRUCTURE_3t06| PDB=3t06 | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ARHGB_HUMAN ARHGB_HUMAN] May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.
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===Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA===
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==See Also==
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*[[Rho GTPase 3D structures|Rho GTPase 3D structures]]
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*[[Rho guanine nucleotide exchange factor 3D structures|Rho guanine nucleotide exchange factor 3D structures]]
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==About this Structure==
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__TOC__
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[[3t06]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3T06 OCA].
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Bielnicki, J A.]]
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[[Category: Large Structures]]
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[[Category: Derewenda, U.]]
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[[Category: Bielnicki JA]]
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[[Category: Derewenda, Z S.]]
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[[Category: Derewenda U]]
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[[Category: Dh-ph rhoa complex]]
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[[Category: Derewenda ZS]]
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[[Category: Guanine nucleotide exchange factor]]
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[[Category: Pdzrhogef]]
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[[Category: Rhoa]]
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[[Category: Signaling protein]]
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Current revision

Crystal Structure of the DH/PH fragment of PDZRHOGEF with N-terminal regulatory elements in complex with Human RhoA

PDB ID 3t06

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