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1eem

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{{Seed}}
 
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[[Image:1eem.png|left|200px]]
 
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<!--
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==GLUTATHIONE TRANSFERASE FROM HOMO SAPIENS==
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The line below this paragraph, containing "STRUCTURE_1eem", creates the "Structure Box" on the page.
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<StructureSection load='1eem' size='340' side='right'caption='[[1eem]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1eem]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EEM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1EEM FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GSH:GLUTATHIONE'>GSH</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1eem| PDB=1eem | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1eem FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1eem OCA], [https://pdbe.org/1eem PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1eem RCSB], [https://www.ebi.ac.uk/pdbsum/1eem PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1eem ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GSTO1_HUMAN GSTO1_HUMAN] Exhibits glutathione-dependent thiol transferase and dehydroascorbate reductase activities. Has S-(phenacyl)glutathione reductase activity. Has also glutathione S-transferase activity. Participates in the biotransformation of inorganic arsenic and reduces monomethylarsonic acid (MMA) and dimethylarsonic acid.<ref>PMID:10783391</ref> <ref>PMID:11511179</ref> <ref>PMID:17226937</ref> <ref>PMID:18028863</ref> <ref>PMID:21106529</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ee/1eem_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1eem ConSurf].
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<div style="clear:both"></div>
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===GLUTATHIONE TRANSFERASE FROM HOMO SAPIENS===
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==See Also==
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*[[Glutathione S-transferase 3D structures|Glutathione S-transferase 3D structures]]
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== References ==
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<!--
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<references/>
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The line below this paragraph, {{ABSTRACT_PUBMED_10783391}}, adds the Publication Abstract to the page
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__TOC__
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(as it appears on PubMed at http://www.pubmed.gov), where 10783391 is the PubMed ID number.
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</StructureSection>
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-->
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{{ABSTRACT_PUBMED_10783391}}
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==About this Structure==
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1EEM is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1EEM OCA].
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==Reference==
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Identification, characterization, and crystal structure of the Omega class glutathione transferases., Board PG, Coggan M, Chelvanayagam G, Easteal S, Jermiin LS, Schulte GK, Danley DE, Hoth LR, Griffor MC, Kamath AV, Rosner MH, Chrunyk BA, Perregaux DE, Gabel CA, Geoghegan KF, Pandit J, J Biol Chem. 2000 Aug 11;275(32):24798-806. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10783391 10783391]
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Board, P.]]
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[[Category: Board P]]
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[[Category: Chelvanayagam, G.]]
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[[Category: Chelvanayagam G]]
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[[Category: Chrunyk, B A.]]
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[[Category: Chrunyk BA]]
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[[Category: Coggan, M.]]
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[[Category: Coggan M]]
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[[Category: Danley, D E.]]
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[[Category: Danley DE]]
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[[Category: Easteal, S.]]
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[[Category: Easteal S]]
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[[Category: Gabel, C A.]]
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[[Category: Gabel CA]]
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[[Category: Geoghegan, K F.]]
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[[Category: Geoghegan KF]]
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[[Category: Griffor, M C.]]
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[[Category: Griffor MC]]
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[[Category: Hoth, L R.]]
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[[Category: Hoth LR]]
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[[Category: Jermiin, L S.]]
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[[Category: Jermiin LS]]
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[[Category: Kamath, A V.]]
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[[Category: Kamath AV]]
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[[Category: Pandit, J.]]
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[[Category: Pandit J]]
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[[Category: Perregaux, D E.]]
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[[Category: Perregaux DE]]
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[[Category: Rosner, M H.]]
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[[Category: Rosner MH]]
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[[Category: Schulte, G K.]]
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[[Category: Schulte GK]]
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[[Category: Glutathione conjugating]]
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[[Category: Gst]]
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[[Category: Putative oxidoreductase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 1 00:34:42 2008''
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Current revision

GLUTATHIONE TRANSFERASE FROM HOMO SAPIENS

PDB ID 1eem

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