This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1tx6

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:45, 1 May 2024) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 1: Line 1:
-
{{Seed}}
 
-
[[Image:1tx6.png|left|200px]]
 
-
<!--
+
==trypsin:BBI complex==
-
The line below this paragraph, containing "STRUCTURE_1tx6", creates the "Structure Box" on the page.
+
<StructureSection load='1tx6' size='340' side='right'caption='[[1tx6]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
-
You may change the PDB parameter (which sets the PDB file loaded into the applet)
+
== Structural highlights ==
-
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
+
<table><tr><td colspan='2'>[[1tx6]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare] and [https://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TX6 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1TX6 FirstGlance]. <br>
-
or leave the SCENE parameter empty for the default display.
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
-
-->
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene></td></tr>
-
{{STRUCTURE_1tx6| PDB=1tx6 | SCENE= }}
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1tx6 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1tx6 OCA], [https://pdbe.org/1tx6 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1tx6 RCSB], [https://www.ebi.ac.uk/pdbsum/1tx6 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1tx6 ProSAT]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/TRYP_PIG TRYP_PIG]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/tx/1tx6_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1tx6 ConSurf].
 +
<div style="clear:both"></div>
-
===trypsin:BBI complex===
+
==See Also==
-
 
+
*[[Trypsin 3D structures|Trypsin 3D structures]]
-
 
+
*[[Trypsin inhibitor 3D structures|Trypsin inhibitor 3D structures]]
-
<!--
+
__TOC__
-
The line below this paragraph, {{ABSTRACT_PUBMED_15381428}}, adds the Publication Abstract to the page
+
</StructureSection>
-
(as it appears on PubMed at http://www.pubmed.gov), where 15381428 is the PubMed ID number.
+
-
-->
+
-
{{ABSTRACT_PUBMED_15381428}}
+
-
 
+
-
==About this Structure==
+
-
1TX6 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Hordeum_vulgare Hordeum vulgare] and [http://en.wikipedia.org/wiki/Sus_scrofa Sus scrofa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1TX6 OCA].
+
-
 
+
-
==Reference==
+
-
Crystal structure of the Bowman-Birk inhibitor from barley seeds in ternary complex with porcine trypsin., Park EY, Kim JA, Kim HW, Kim YS, Song HK, J Mol Biol. 2004 Oct 8;343(1):173-86. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15381428 15381428]
+
-
 
+
-
Crystal structure of a 16 kDa double-headed Bowman-Birk trypsin inhibitor from barley seeds at 1.9 A resolution., Song HK, Kim YS, Yang JK, Moon J, Lee JY, Suh SW, J Mol Biol. 1999 Nov 12;293(5):1133-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10547291 10547291]
+
-
 
+
-
Crystallization and preliminary X-ray analysis of a complex between the Bowman-Birk trypsin inhibitor from barley and porcine pancreatic trypsin., Kim YS, Song HK, Suh SW, Acta Crystallogr D Biol Crystallogr. 1999 Jun;55(Pt 6):1244-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/10329799 10329799]
+
[[Category: Hordeum vulgare]]
[[Category: Hordeum vulgare]]
-
[[Category: Protein complex]]
+
[[Category: Large Structures]]
[[Category: Sus scrofa]]
[[Category: Sus scrofa]]
-
[[Category: Kim, H W.]]
+
[[Category: Kim HW]]
-
[[Category: Kim, J A.]]
+
[[Category: Kim JA]]
-
[[Category: Kim, Y S.]]
+
[[Category: Kim YS]]
-
[[Category: Park, E Y.]]
+
[[Category: Park EY]]
-
[[Category: Song, H K.]]
+
[[Category: Song HK]]
-
[[Category: Anticarcinogenic activity]]
+
-
[[Category: Double-headed inhibitor]]
+
-
[[Category: Gene duplication]]
+
-
[[Category: Inhibitory loop]]
+
-
[[Category: Monocotyledonous plant]]
+
-
 
+
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Tue Jul 29 12:32:07 2008''
+

Current revision

trypsin:BBI complex

PDB ID 1tx6

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools