8rcx

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'''Unreleased structure'''
 
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The entry 8rcx is ON HOLD until sometime in the future
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==Crystal structure of the Mycobacterium tuberculosis regulator VirS (N-terminal fragment 4-208) in complex with the drug candidate alpibectir==
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<StructureSection load='8rcx' size='340' side='right'caption='[[8rcx]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
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Authors: Edoo, Z., Frita, R., Grosse, C., Bourotte, M., Moune, M., Antoine, R., Trebosc, V., Schellhorn, B., Dreneau, A., Hofmann, L., Kemmer, C., Lociuro, S., Dale, G.E., Jung, F., Perez-Herran, E., Mendoza, A., Rebollo Lopez, M.J., Ghidelli-Disse, S., Drewes, G., Mathys, V., Soetaert, K., Megalizzi, V., Wintjens, R., Barros Aguirre, D., Remuinan, M.D., Gitzinger, M., Deprez, B., Willand, N., Pieren, M., Baulard, A.R.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8rcx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8RCX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8RCX FirstGlance]. <br>
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Description: Crystal structure of the Mycobacterium tuberculosis regulator VirS (N-terminal fragment 4-208) in complex with the drug candidate alpibectir
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.494&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=YPQ:4,4,4-tris(fluoranyl)-1-[3-(trifluoromethyl)-1-oxa-2,8-diazaspiro[4.5]dec-2-en-8-yl]butan-1-one'>YPQ</scene></td></tr>
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[[Category: Pieren, M]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8rcx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8rcx OCA], [https://pdbe.org/8rcx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8rcx RCSB], [https://www.ebi.ac.uk/pdbsum/8rcx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8rcx ProSAT]</span></td></tr>
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[[Category: Mendoza, A]]
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</table>
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[[Category: Kemmer, C]]
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== Function ==
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[[Category: Antoine, R]]
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[https://www.uniprot.org/uniprot/VIRS_MYCTU VIRS_MYCTU] Regulates the expression of the mymA operon (Rv3083-Rv3089).<ref>PMID:14568148</ref>
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[[Category: Frita, R]]
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== References ==
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[[Category: Barros Aguirre, D]]
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<references/>
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[[Category: Perez-Herran, E]]
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__TOC__
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[[Category: Hofmann, L]]
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</StructureSection>
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[[Category: Baulard, A.R]]
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[[Category: Large Structures]]
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[[Category: Remuinan, M.D]]
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[[Category: Mycobacterium tuberculosis H37Rv]]
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[[Category: Soetaert, K]]
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[[Category: Antoine R]]
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[[Category: Ghidelli-Disse, S]]
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[[Category: Barros Aguirre D]]
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[[Category: Willand, N]]
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[[Category: Baulard AR]]
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[[Category: Grosse, C]]
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[[Category: Bourotte M]]
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[[Category: Bourotte, M]]
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[[Category: Dale GE]]
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[[Category: Jung, F]]
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[[Category: Deprez B]]
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[[Category: Dale, G.E]]
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[[Category: Dreneau A]]
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[[Category: Wintjens, R]]
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[[Category: Drewes G]]
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[[Category: Lociuro, S]]
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[[Category: Edoo Z]]
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[[Category: Moune, M]]
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[[Category: Frita R]]
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[[Category: Dreneau, A]]
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[[Category: Ghidelli-Disse S]]
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[[Category: Gitzinger, M]]
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[[Category: Gitzinger M]]
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[[Category: Megalizzi, V]]
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[[Category: Grosse C]]
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[[Category: Drewes, G]]
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[[Category: Hofmann L]]
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[[Category: Rebollo Lopez, M.J]]
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[[Category: Jung F]]
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[[Category: Deprez, B]]
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[[Category: Kemmer C]]
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[[Category: Mathys, V]]
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[[Category: Lociuro S]]
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[[Category: Edoo, Z]]
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[[Category: Mathys V]]
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[[Category: Schellhorn, B]]
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[[Category: Megalizzi V]]
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[[Category: Trebosc, V]]
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[[Category: Mendoza A]]
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[[Category: Moune M]]
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[[Category: Perez-Herran E]]
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[[Category: Pieren M]]
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[[Category: Rebollo Lopez MJ]]
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[[Category: Remuinan MD]]
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[[Category: Schellhorn B]]
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[[Category: Soetaert K]]
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[[Category: Trebosc V]]
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[[Category: Willand N]]
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[[Category: Wintjens R]]

Current revision

Crystal structure of the Mycobacterium tuberculosis regulator VirS (N-terminal fragment 4-208) in complex with the drug candidate alpibectir

PDB ID 8rcx

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OCA

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