3qpk

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[[Image:3qpk.png|left|200px]]
 
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==Probing oxygen channels in Melanocarpus albomyces laccase==
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The line below this paragraph, containing "STRUCTURE_3qpk", creates the "Structure Box" on the page.
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<StructureSection load='3qpk' size='340' side='right'caption='[[3qpk]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3qpk]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPK OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3QPK FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=CU:COPPER+(II)+ION'>CU</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=XE:XENON'>XE</scene></td></tr>
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{{STRUCTURE_3qpk| PDB=3qpk | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3qpk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3qpk OCA], [https://pdbe.org/3qpk PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3qpk RCSB], [https://www.ebi.ac.uk/pdbsum/3qpk PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3qpk ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/LAC1_MELAO LAC1_MELAO] Lignin degradation and detoxification of lignin-derived products (Probable).<ref>PMID:15474046</ref>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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Laccases catalyze the oxidation of phenolic substrates and the concominant reduction of dioxygen to water. We used xenon as an oxygen probe in search of routes for the entry of dioxygen into the catalytic center. Two xenon-pressurized crystal structures of recombinant Melanocarpus albomyces laccase were determined, showing three hydrophobic Xe-binding sites located in domain C. The analysis of hydrophobic cavities in other laccase structures further suggested the preference of domain C for binding of hydrophobic species such as dioxygen, thus suggesting that the hydrophobic core of domain C could function as a channel through which dioxygen can enter the trinuclear copper center.
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===Probing oxygen channels in Melanocarpus albomyces laccase===
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Probing the Dioxygen Route in Melanocarpus albomyces Laccase with Pressurized Xenon Gas.,Kallio JP, Rouvinen J, Kruus K, Hakulinen N Biochemistry. 2011 May 5. PMID:21524088<ref>PMID:21524088</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 3qpk" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_21524088}}, adds the Publication Abstract to the page
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*[[Laccase 3D structures|Laccase 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 21524088 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_21524088}}
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__TOC__
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</StructureSection>
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==About this Structure==
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[[Category: Large Structures]]
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[[3qpk]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Melanocarpus_albomyces Melanocarpus albomyces]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3QPK OCA].
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==Reference==
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<ref group="xtra">PMID:021524088</ref><references group="xtra"/>
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[[Category: Laccase]]
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[[Category: Melanocarpus albomyces]]
[[Category: Melanocarpus albomyces]]
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[[Category: Hakulinen, N.]]
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[[Category: Hakulinen N]]
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[[Category: Kallio, J P.]]
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[[Category: Kallio JP]]
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[[Category: Rouvinen, J.]]
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[[Category: Rouvinen J]]

Current revision

Probing oxygen channels in Melanocarpus albomyces laccase

PDB ID 3qpk

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