Xylosidase

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<StructureSection load='2xvl' size='350' side='right' caption='Structure of α-xylosidase family 31 complex with xylobiose, sulfate, Ni+2 and Cl- ions (PDB entry [[2xvl]])' scene=''>
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<StructureSection load='' size='350' side='right' caption='Structure of α-xylosidase family 31 complex with pentaerythritol propoxylate, sulfate, Ni+2 (small green) and Cl- (large green) ions (PDB entry [[2xvl]])' scene='55/551220/Cv/1'>
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__TOC__
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== Function ==
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'''Xylosidase''' (XYL) catalyzes the hydrolysis of α- or β-glycosidic linkages.
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'''Xylosidase''' (XYL) catalyzes the hydrolysis of α- or β-glycosidic linkages. Β-XYL catalyzes the endo-hydrolysis of 1,4-β-D-glycosidic or endo-hydrolysis of 1,3-β-D-glycosidic linkage. Α-XYL catalyzes the exo-hydrolysis of 1,4-β-D-glycosidic or exo-hydrolysis of 1,3-β-D-glycosidic linkage from the non-reducing termini of xylans. XYL catalyzes the conversion of cellulose and hemicellulose xylan to xylose.
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*'''α-XYL''' catalyzes the exo-hydrolysis of 1,4-β-D-glycosidic or exo-hydrolysis of 1,3-β-D-glycosidic linkage from the non-reducing termini of xylans<ref>PMID:10801892</ref>. XYL catalyzes the conversion of cellulose and hemicellulose xylan to xylose.
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*'''β-XYL''' catalyzes the endo-hydrolysis of 1,4-β-D-glycosidic or endo-hydrolysis of 1,3-β-D-glycosidic linkage<ref>PMID:15283123</ref>.
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*'''α-XYL family 31''' catalyzes the hydrolysis of α-xylosyl from isoprimeverose<ref>PMID:35441671</ref>.
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*'''β-XYL family 3''' catalyzes the endo-hydrolysis of 1,4-β-D-glycosidic or endo-hydrolysis of 1,3-β-D-glycosidic linkage<ref>PMID:35120929</ref>.
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*'''β-XYL family 43''' and '''β-XYL family 52''' degrade xylooligosaccharides<ref>PMID:26494804</ref>, <ref>PMID:12738774</ref>.
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*'''β-XYL family 120''' degrades xylobiose and xylotriose<ref>PMID:31698702</ref>.
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*'''β-XYL/glucosidase''' bifunctional enzyme active on beta-xylosides and beta-glucosides.
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== Structural highlights ==
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The <scene name='55/551220/Cv/5'>active site of α-xylosidase contains the xyloglucan and nucleophilic water</scene><ref>PMID:21426303</ref>. Water molecules are shown as red spheres. <scene name='55/551220/Cv/6'>Ni/Cl complex</scene>.
== 3D Structures of xylosidase ==
== 3D Structures of xylosidase ==
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[[Xylosidase 3D structures]]
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Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}}
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==References==
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<references />
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'''α-xylosidase family 31'''
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</StructureSection>
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[[2xvg]], [[2xvk]] – CjXYL – ''Cellvibrio japonicus'' <BR />
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[[2xvl]] – CjXYL + xylobiose <BR />
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[[1xsi]], [[1xsj]], [[1we5]] – EcXYL – Escherichia coli<br />
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[[1xsk]] – EcXYL + intermediate<br />
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'''β-xylosidase'''
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[[1yrz]] – XYL – ''Bacillus halodurans'' <BR />
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[[1yif]] – XYL – ''Bacillus subtilis'' <BR />
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[[3c2u]] – XYL + propane derivative – ''Selenomonas ruminantium'' <BR />
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'''β-xylosidase family 39'''
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[[1px8]], [[1uhv]] – TsXYL – ''Thermoanaerobacterium saccharolyticum'' <BR />
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[[4ekj]] – XYL – Caulobacter vibrioides<BR />
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[[2bs9]], [[1w91]] – BsXYL – ''Bacillus stearothermophilus'' <BR />
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[[2bfg]] – BsXYL + xylobiose <BR />
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'''β-xylosidase family 43'''
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[[1y7b]], [[1yi7]], [[3k1u]] – CaXYL – ''Clostridium acetobutylicum'' <BR />
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[[3qed]], [[3qee]] – CjXYL <BR />
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[[2exh]] – BsXYL <BR />
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[[2exi]] – BsXYL (mutant) <BR />
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[[2exj]] – BsXYL + xylobiose <BR />
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[[2exk]] – BsXYL (mutant) + xylobiose <BR />
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[[3qef]] – CaXYL (mutant) + arabinofuranose <BR />
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'''β-xylosidase family 120'''
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[[3vst]] – TsXYL <BR />
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[[3vsv]] – TsXYL + xylose <BR />
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[[3vsu]] – TsXYL + xylobiose <BR />
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[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

Structure of α-xylosidase family 31 complex with pentaerythritol propoxylate, sulfate, Ni+2 (small green) and Cl- (large green) ions (PDB entry 2xvl)

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Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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