3rsh

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==Structure of 3-ketoacyl-(acyl-carrier-protein)reductase (FabG) from Vibrio cholerae O1 complexed with NADP+ (space group P62)==
==Structure of 3-ketoacyl-(acyl-carrier-protein)reductase (FabG) from Vibrio cholerae O1 complexed with NADP+ (space group P62)==
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<StructureSection load='3rsh' size='340' side='right' caption='[[3rsh]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
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<StructureSection load='3rsh' size='340' side='right'caption='[[3rsh]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3rsh]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Vibrio_cholerae_o1_biovar_el_tor Vibrio cholerae o1 biovar el tor]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RSH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3RSH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3rsh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Vibrio_cholerae_O1_biovar_El_Tor_str._N16961 Vibrio cholerae O1 biovar El Tor str. N16961]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3RSH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3RSH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[3op4|3op4]], [[3rro|3rro]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAP:NADP+NICOTINAMIDE-ADENINE-DINUCLEOTIDE+PHOSPHATE'>NAP</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">VCD_002346 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=686 Vibrio cholerae O1 biovar El Tor])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3rsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rsh OCA], [https://pdbe.org/3rsh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3rsh RCSB], [https://www.ebi.ac.uk/pdbsum/3rsh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3rsh ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/3-oxoacyl-[acyl-carrier-protein]_reductase 3-oxoacyl-[acyl-carrier-protein] reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.100 1.1.1.100] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3rsh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3rsh OCA], [http://www.rcsb.org/pdb/explore.do?structureId=3rsh RCSB], [http://www.ebi.ac.uk/pdbsum/3rsh PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FABG_VIBCH FABG_VIBCH] Catalyzes the NADPH-dependent reduction of beta-ketoacyl-ACP substrates to beta-hydroxyacyl-ACP products, the first reductive step in the elongation cycle of fatty acid biosynthesis.
==See Also==
==See Also==
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*[[Beta-ketoacyl-ACP reductase|Beta-ketoacyl-ACP reductase]]
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*[[Beta-ketoacyl carrier protein reductase 3D structures|Beta-ketoacyl carrier protein reductase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Vibrio cholerae o1 biovar el tor]]
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[[Category: Large Structures]]
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[[Category: Anderson, W]]
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[[Category: Vibrio cholerae O1 biovar El Tor str. N16961]]
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[[Category: Structural genomic]]
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[[Category: Anderson W]]
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[[Category: Chruszcz, M]]
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[[Category: Chruszcz M]]
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[[Category: Cooper, D R]]
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[[Category: Cooper DR]]
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[[Category: Grabowski, M]]
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[[Category: Grabowski M]]
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[[Category: Hou, J]]
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[[Category: Hou J]]
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[[Category: Minor, W]]
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[[Category: Minor W]]
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[[Category: Osinski, T]]
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[[Category: Osinski T]]
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[[Category: Shumilin, I]]
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[[Category: Shumilin I]]
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[[Category: Zheng, H]]
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[[Category: Zheng H]]
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[[Category: Acyl carrier protein]]
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[[Category: Cell plasma]]
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[[Category: Csgid]]
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[[Category: Fabg]]
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[[Category: Oxidoreductase]]
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[[Category: Oxireductase]]
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Current revision

Structure of 3-ketoacyl-(acyl-carrier-protein)reductase (FabG) from Vibrio cholerae O1 complexed with NADP+ (space group P62)

PDB ID 3rsh

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