Peptide N-glycanase

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PNG F is used in studying of glycoproteins.
PNG F is used in studying of glycoproteins.
== Structural highlights ==
== Structural highlights ==
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*<scene name='68/684794/Cv/2'>Zn coordination site contains 4 cysteins</scene>.
+
*<scene name='68/684794/Cv/5'>Zn coordination site contains 4 cysteins</scene>.
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*<scene name='68/684794/Cv/3'>Cl coordination site</scene>.
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*<scene name='68/684794/Cv/6'>Cl coordination site</scene>.
</StructureSection>
</StructureSection>
== 3D Structures of PNGase ==
== 3D Structures of PNGase ==
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*PNGase F
*PNGase F
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**[[1pgs]], [[1png]] – EmPNG – ''Elizabethkingia meningoseptica''<br />
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**[[1pgs]], [[1png]], [[3pms]] – EmPNG – ''Elizabethkingia meningoseptica''<br />
 +
**[[4r4x]], [[4r4z]] – EmPNG-II<br />
**[[1pnf]] – EmPNG + acetylchitobiose <br />
**[[1pnf]] – EmPNG + acetylchitobiose <br />
}}
}}

Current revision

Yeast PNGase catalytic domain (sky blue) complex with Rad23 (green), Zn+2 (grey) and Cl- (green) ions (PDB code 2f4m).

Drag the structure with the mouse to rotate

3D Structures of PNGase

Updated on 22-August-2023

References

  1. Tanabe K, Lennarz WJ, Suzuki T. A cytoplasmic peptide: N-glycanase. Methods Enzymol. 2006;415:46-55. PMID:17116467 doi:http://dx.doi.org/10.1016/S0076-6879(06)15004-1
  2. Norris GE, Stillman TJ, Anderson BF, Baker EN. The three-dimensional structure of PNGase F, a glycosylasparaginase from Flavobacterium meningosepticum. Structure. 1994 Nov 15;2(11):1049-59. PMID:7881905
  3. Suzuki T. The cytoplasmic peptide:N-glycanase (Ngly1)-basic science encounters a human genetic disorder. J Biochem. 2015 Jan;157(1):23-34. doi: 10.1093/jb/mvu068. Epub 2014 Nov 13. PMID:25398991 doi:http://dx.doi.org/10.1093/jb/mvu068

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