Tripeptidyl peptidase
From Proteopedia
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| - | [[Tripeptidyl peptidase]] (TPP) is an enzyme which cleaves N-terminal tripeptides from polypeptides. TPP-I functions in lysosomes, TPP-II is part of the ubiquitin-proteasome pathway. | + | [[Tripeptidyl peptidase]] (TPP) is an enzyme which cleaves N-terminal tripeptides from polypeptides. TPP-I functions in lysosomes, TPP-II is part of the ubiquitin-proteasome pathway. |
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== 3D Structures of Tripeptidyl peptidase == | == 3D Structures of Tripeptidyl peptidase == | ||
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===TPP-I=== | ===TPP-I=== | ||
Revision as of 08:04, 21 August 2014
Image:2d5l.png
Crystal Structure of Tripeptidyl peptidase (2d5l)
Tripeptidyl peptidase (TPP) is an enzyme which cleaves N-terminal tripeptides from polypeptides. TPP-I functions in lysosomes, TPP-II is part of the ubiquitin-proteasome pathway.
Contents |
3D Structures of Tripeptidyl peptidase
TPP-I
3ee6 – TPP-I – human
3edy – hTPP-I precursor residues 20-563
TPP-II
3lxu – TPP-II residues 463-770 – Drosophila melanogaster
TPP-IV
2eep – PgPro-TPP-IV+inhibitor – Porphyromonas gingivalis
2d5l - PgPro-TPP-IV
2z3w - PgPro-TPP-IV (mutant)
2z3z, 2dcm - PgPro-TPP-IV (mutant)+inhibitor
