Molecular Playground/ClyA

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==About this Structure==
==About this Structure==
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[[1QOY]] is a monomer from the dodecameric pore-forming toxin from [http://en.wikipedia.org/wiki/Escherichia_coli ''Escherichia coli'']. It is comprised of four alpha helicies and a smaller fifth alpha helix.
 
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Though its crystal structure, [[Image:ClyA.png]] [[2WCD]] revealed a dodecamer, larger [http://pubs.acs.org/doi/abs/10.1021/ja4053398 pores] have been isolated, as well.
 
[[Image:ClyA-monomer.png]]
[[Image:ClyA-monomer.png]]
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[[1QOY]] is a monomer from the dodecameric pore-forming toxin from [http://en.wikipedia.org/wiki/Escherichia_coli ''Escherichia coli'']. It is comprised of four alpha helicies and a smaller fifth alpha helix.
 +
Though its crystal structure,[[2WCD]] revealed a dodecamer, larger [http://pubs.acs.org/doi/abs/10.1021/ja4053398 pores] have been isolated, as well.
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[[Image:ClyA.png]]
==Research on ClyA at UMass Amherst==
==Research on ClyA at UMass Amherst==
The Chen Lab, in collaboration with the Heuck lab, recently published a paper on [http://www.jbc.org/content/288/43/31042.short, ClyA] assembly.
The Chen Lab, in collaboration with the Heuck lab, recently published a paper on [http://www.jbc.org/content/288/43/31042.short, ClyA] assembly.

Revision as of 16:31, 26 March 2014

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Bib Yang, Michal Harel, Monifa Fahie

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