Sialyltransferase

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*Sialyltransferase
*Sialyltransferase
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**[[4r83]] – PhdSIT 0160 – ''Photobacterium damsela''<br />
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**[[4r84]] – PhdSIT 0160 + CMP derivative<br />
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**[[4r9v]] – PhdSIT 0160 + gt-b domain<br />
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 +
*Alpha-2,3-sialyltransferase
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**[[4v2u]], [[4v39]] – PdSIT – ''Pasteurella dagmatis''<br />
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**[[4v38]] – PdSIT (mutant)<br />
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**[[4v3b]], [[4v3c]] – PdSIT + CMP<br />
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**[[2ex0]] – PmSIT - ''Pasteurella multocida''<br />
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**[[2iy7]], [[2ihj]], [[2ihk]], [[2ex1]] – PmSIT + CMP derivative <br />
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**[[2c84]] – PmSIT + CMP <br />
 +
**[[2iy8]], [[2ihz]], [[2ilv]] – PmSIT + CMP derivative + lactose<br />
 +
**[[2ii6]], [[2iib]], [[2iiq]], [[3s44]] – PmSIT (mutant) + CMP derivative <br />
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**[[2p56]] – CjSIT II – ''Campylobacter jejuni''<br />
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**[[2x61]] – CjSIT II + sialic acid + CMP <br />
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**[[2x62]], [[2x63]], [[2wqq]], [[2drj]] – CjSIT II (mutant) + CMP <br />
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**[[1ro7]], [[1ro8]] – CjSIT II + CMP derivative<br />
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**[[2p2v]] – CjSIT I + CMP derivative<BR />
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**[[2wml]], [[2wnf]] – pSIT – pig <BR />
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**[[2wnb]] – pSIT + CMP + disaccharide <BR />
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**[[2yk4]] – NmSIT – ''Neisseria meningitidis'' <BR />
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**[[2yk5]], [[2yk7]] – NmSIT + CMP derivative<BR />
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**[[2yk6]] – NmSIT + CDP<BR />
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**[[2zwi]] – SIT + CMP – ''Photobacterium phosphoreum'' <BR />
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*Alpha-2,6-sialyltransferase
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 +
**[[4mps]] – SIT – rat <BR />
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**[[4js1]] – hSIT 1 catalytic domain + cytidine + Pi<BR />
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**[[4js2]] – hSIT 1 catalytic domain + CMP<BR />
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*Alpha-2,8-sialyltransferase
**[[5bo8]] – hSIT - human<br />
**[[5bo8]] – hSIT - human<br />
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**[[4r84]] – PhdSIT + CMP derivative<br />
**[[4r84]] – PhdSIT + CMP derivative<br />
**[[4r9v]] – PhdSIT + gt-b domain<br />
**[[4r9v]] – PhdSIT + gt-b domain<br />
- 
-
*Alpha-2,3-sialyltransferase
 
- 
-
**[[4v2u]], [[4v38]], [[4v39]] – PdSIT – ''Pasteurella dagmatis''<br />
 
-
**[[4v3b]], [[4v3c]] – PdSIT + CMP<br />
 
-
**[[2ex0]] – PmSIT - ''Pasteurella multocida''<br />
 
-
**[[3s44]], [[2iy7]], [[2ihj]], [[2ihk]], [[2ex1]] – PmSIT + CMP derivative <br />
 
-
**[[2c84]] – PmSIT + CMP <br />
 
-
**[[2iy8]], [[2ihz]], [[2ilv]] – PmSIT + CMP derivative + lactose<br />
 
-
**[[2ii6]], [[2iib]], [[2iiq]] – PmSIT (mutant) + CMP derivative <br />
 
-
**[[2p2v]], [[2p56]] – CjSIT – ''Campylobacter jejuni''<br />
 
-
**[[2x61]] – CjSIT + sialic acid + CMP <br />
 
-
**[[2x62]], [[2x63]], [[2wqq]], [[2drj]] – CjSIT (mutant) + CMP <br />
 
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**[[1ro7]], [[1ro8]] – CjSIT + CMP derivative<br />
 
}}
}}
== References ==
== References ==
<references/>
<references/>
[[Category:Topic Page]]
[[Category:Topic Page]]

Revision as of 10:23, 19 November 2018

α-2,3-sialyltransferase complex with trisaccharide, acetate, MPD and ethylene glycol (PDB code 2x61)

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3D structures of sialyltransferase

Updated on 19-November-2018

References

  1. Schwartz-Albiez R, Merling A, Martin S, Haas R, Gross HJ. Cell surface sialylation and ecto-sialyltransferase activity of human CD34 progenitors from peripheral blood and bone marrow. Glycoconj J. 2004;21(8-9):451-9. PMID:15750786 doi:http://dx.doi.org/10.1007/s10719-004-5535-5
  2. Harduin-Lepers A, Vallejo-Ruiz V, Krzewinski-Recchi MA, Samyn-Petit B, Julien S, Delannoy P. The human sialyltransferase family. Biochimie. 2001 Aug;83(8):727-37. PMID:11530204
  3. Wang L, Liu Y, Wu L, Sun XL. Sialyltransferase inhibition and recent advances. Biochim Biophys Acta. 2016 Jan;1864(1):143-53. doi: 10.1016/j.bbapap.2015.07.007., Epub 2015 Jul 18. PMID:26192491 doi:http://dx.doi.org/10.1016/j.bbapap.2015.07.007
  4. Lee HJ, Lairson LL, Rich JR, Lameignere E, Wakarchuk WW, Withers SG, Strynadka NC. Structural and kinetic analysis of substrate binding to the sialyltransferase CST-II from Campylobacter Jejuni. J Biol Chem. 2011 Aug 8. PMID:21832050 doi:10.1074/jbc.M111.261172

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