User:Tilman Schirmer/Sandbox 201
From Proteopedia
(Difference between revisions)
(→Primary and secondary inhibition sites) |
|||
| Line 1: | Line 1: | ||
'''''Diguanylate cyclases''''' | '''''Diguanylate cyclases''''' | ||
| - | == | + | == PleD == |
| - | === | + | === Intro === |
---- | ---- | ||
| - | === | + | === Domain structure === |
| Line 13: | Line 13: | ||
---- | ---- | ||
| - | === | + | === Protomer === |
<applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/Protomer_activeated/1' size='300' frame='true' align='right' caption='2v0n' /> | <applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/Protomer_activeated/1' size='300' frame='true' align='right' caption='2v0n' /> | ||
| Line 22: | Line 22: | ||
---- | ---- | ||
| - | === | + | === Substrate binding site === |
<applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/Substrate_binding_site/2' size='300' frame='true' align='right' caption='2v0n' /> | <applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/Substrate_binding_site/2' size='300' frame='true' align='right' caption='2v0n' /> | ||
| Line 34: | Line 34: | ||
---- | ---- | ||
| - | === | + | === Allosteric product binding site === |
<applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/5gp/1' size='300' frame='true' align='right' caption='Insert caption here' /> | <applet load='2v0n' scene='User:Tilman_Schirmer/Sandbox_201/5gp/1' size='300' frame='true' align='right' caption='Insert caption here' /> | ||
---- | ---- | ||
| Line 68: | Line 68: | ||
---- | ---- | ||
| - | === | + | === Two conformations === |
[[Image:1w25_small.png|frame|left|non-activated (1w25)]] [[Image:2v0n_small_smaller2.png|frame|center|activated (BeF3- modified; 2v0n)]] | [[Image:1w25_small.png|frame|left|non-activated (1w25)]] [[Image:2v0n_small_smaller2.png|frame|center|activated (BeF3- modified; 2v0n)]] | ||
| Line 77: | Line 77: | ||
---- | ---- | ||
| - | === | + | === Non-activated conformation === |
[[1w25]] | [[1w25]] | ||
| Line 93: | Line 93: | ||
---- | ---- | ||
| - | === | + | === Activated conformation === |
[[2v0n]] | [[2v0n]] | ||
| Line 106: | Line 106: | ||
<br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br> | <br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br><br> | ||
---- | ---- | ||
| - | |||
| - | == 2. WspR == | ||
Revision as of 13:09, 19 June 2009
Diguanylate cyclases
Contents |
PleD
Intro
Domain structure
Protomer
|
: , ,
Substrate binding site
|
Allosteric product binding site
|
C-di-GMP
Primary inhibition site (Ip)
Secondary inhibition site (Is)
Primary and secondary inhibition sites
Two conformations
non-activated (1w25)
activated (BeF3- modified; 2v0n)
|
|
Non-activated conformation
|
: , ,
Activated conformation
|
