Thioredoxin Reductase
From Proteopedia
| Line 16: | Line 16: | ||
[[1cl0]], [[1tde]], [[1trb]] – EcTrxR+FAD – ''Eschericia coli''<br /> | [[1cl0]], [[1tde]], [[1trb]] – EcTrxR+FAD – ''Eschericia coli''<br /> | ||
[[1tdf]] - EcTrxR+FAD+NADPH<br /> | [[1tdf]] - EcTrxR+FAD+NADPH<br /> | ||
| + | [[1f6m]] - EcTrxR (mutant)+Trx-1+FAD+AADPH<br /> | ||
[[1h6v]] – rTrxR (mutant)+FAD+NADPH – rat<br /> | [[1h6v]] – rTrxR (mutant)+FAD+NADPH – rat<br /> | ||
[[1vdc]] – TrxR+FAD – ''Arabidopsis thaliana''<br /> | [[1vdc]] – TrxR+FAD – ''Arabidopsis thaliana''<br /> | ||
Revision as of 14:46, 3 February 2011
Thioredoxin Reductase (TrxR) is an enzyme which reduces thioredoxin using NADPH. TrxR-2 is mitochondrial. The images at the left and at the right correspond to one representative TrxR, i.e. the crystal structure of Thioredoxin Reductase from Eschericia coli (1cl0).
3D Structures of Thioredoxin Reductase
TrxR
1cl0, 1tde, 1trb – EcTrxR+FAD – Eschericia coli
1tdf - EcTrxR+FAD+NADPH
1f6m - EcTrxR (mutant)+Trx-1+FAD+AADPH
1h6v – rTrxR (mutant)+FAD+NADPH – rat
1vdc – TrxR+FAD – Arabidopsis thaliana
2a87 - TrxR+FAD+NADPH – Mycobacterium tuberculosis
3cty - TrxR+FAD – Thermoplasma acidophilum
3d8x - yTrxR+FAD+NADPH - yeast
2nvk - DmTrxR+FAD+NADPH – Drosophila melanogaster
2q0k, 2q0l - HpTrxR+FAD+NADPH – Helicobacter pylori
3ish - HpTrxR+FAD
2q7v - TrxR+FAD – Deinococcus radiodurans
TrxR-1
2cfy – hTrxR-1+FAD – human
2zz0, 2zzb, 2zzc – hTrxR-1 (mutant)+FAD
2j3n – hTrxR-1+FAD+NADPH
3itj – yTrxR-1+FAD
3dh9, 3dgh – DmTrxR-1+FAD
3ean, 3eao – rTrxR-1+FAD+NADPH
TrxR-2
1zdl, 1zkq – mTrxR-2+FAD+NADPH – mouse
3dgz – mTrxR-2+FAD
2whd – TrxR-2+FAD – Hordeum vulgare
TrxR-3
3f8d, 3f8p, 3f8r – TrxR-3 (mutant)+FAD – Sulfolobus solfataricus
3h8q – hTrxR-3 glutaredoxin domain
