User:Michael Kerins/Bovine Odorant Binding Protein
From Proteopedia
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'''''Bovine Odorant Binding Protein''''' | '''''Bovine Odorant Binding Protein''''' | ||
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| - | [[Image:1GT1.jpg|300px|left|thumb| Crystal structure of Bovine Odorant Binding Protein]] [[Image:cow.jpg|300px|right|thumb| Cow]] | + | [[Image:1GT1.jpg|300px|left|thumb| Crystal structure of Bovine Odorant Binding Protein]] [[Image:cow.jpg|300px|right|thumb| Cow]] |
| - | + | Imagine a world without smells: no fresh cookies, no Valentine’s Day roses, and no stinky gym socks. The sense of smell clearly plays a unique role in how humans and other organisms experience their environment. Unlike the physical objects we see and touch, scents travel invisibly through the air, enter our nose, and elicit a sensory perception. The transduction for this sensory mechanism is crucial in eliciting neuronal activity to stimulate the brain. Before transduction is starts, however, select smell molecules, called odorants, must cross a water mucosa layer to reach an extracellular receptor. In bovines, this feat is performed by '''Bovine Odorant Binding Protein (bOBP)''', a small homodimeric protein composed of two β-barrels that utilize a hydrophobic ‘trap’ to transport and release odorants at cellular receptors. | |
| - | <scene name='User:Michael_Kerins/Bovine_Odorant_Binding_Protein/Homodimer/2'>bOBP backbone in blue</scene> | ||
| - | < | + | <scene name='User:Michael_Kerins/Bovine_Odorant_Binding_Protein/Homodimer/2'>bOBP backbone in blue</scene> |
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==The need to smell== | ==The need to smell== | ||
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Revision as of 04:39, 29 April 2011
Bovine Odorant Binding Protein
Imagine a world without smells: no fresh cookies, no Valentine’s Day roses, and no stinky gym socks. The sense of smell clearly plays a unique role in how humans and other organisms experience their environment. Unlike the physical objects we see and touch, scents travel invisibly through the air, enter our nose, and elicit a sensory perception. The transduction for this sensory mechanism is crucial in eliciting neuronal activity to stimulate the brain. Before transduction is starts, however, select smell molecules, called odorants, must cross a water mucosa layer to reach an extracellular receptor. In bovines, this feat is performed by Bovine Odorant Binding Protein (bOBP), a small homodimeric protein composed of two β-barrels that utilize a hydrophobic ‘trap’ to transport and release odorants at cellular receptors.
Contents |
The need to smell
Test
Test
Test
Test
Test
Structure
What are the basic parameters of bOBP?
bOBP is a homodimer of two virtually symmetrical subunits held together noncovalently.
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