Monoamine oxidase
From Proteopedia
| Line 7: | Line 7: | ||
==3D structures of monoamine oxidase == | ==3D structures of monoamine oxidase == | ||
| + | ===MAO-A=== | ||
| + | |||
| + | [[2z5x]], [[2bxr]], [[2bxs]] – hMAO-A + inhibitor + FAD – human<br /> | ||
| + | [[2z5y]] - hMAO-A (mutant) + inhibitor + FAD<br /> | ||
| + | [[1o5w]] - MAO-A + inhibitor + FAD – rat | ||
| + | |||
| + | ===MAO-B=== | ||
| + | |||
| + | [[1gos]] – hMAO-B<br /> | ||
| + | [[3po7]], [[2xcg]], [[2xfn]], [[2xfp]], [[2xfq]], [[2xfu]], [[2vz2]], [[2vrl]], [[2vrm]], [[2v5z]], [[2v60]], [[2v61]], [[2c64]], [[2c65]], [[2c66]], [[2c67]], [[2byb]], [[2bk3]], [[1s2q]], [[1s2y]], [[1s3b]], [[1s3e]], [[1oj9]], [[1oja]], [[1ojc]], [[1ojd]] – hMAO-B + inhibitor + FAD<br /> | ||
| + | [[2xfo]], [[2bk4]], [[2bk5]] - hMAO-B (mutant) + inhibitor + FAD<br /> | ||
| + | [[2c72]], [[2c73]], [[2c75]], [[2c76]] - hMAO-B (mutant) + FAD<br /> | ||
| + | [[2c70]] - hMAO-B + FAD | ||
| + | |||
| + | ===MAO-C=== | ||
| + | |||
| + | [[3qj4]] – hMAO-C + FAD | ||
| + | |||
| + | ===MAO-N=== | ||
| + | |||
| + | [[2vvl]], [[2vvm]] – MAO-N (mutant) + FAD – Aspergillus niger | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 10:26, 20 July 2011
Template:STRUCTURE 2bxr
Monoamine oxidase (MAO) are enzymes which catalyze the oxidation of monoamines. MAO contains FAD as co-factor. MAO-A and MAO-C are human enzymes which oxidize adrenaline, noradrenaline, serotonin and dopamine. MAO-B is a human enzyme which oxidizes benzylamine and phenylethylamine.
3D structures of monoamine oxidase
MAO-A
2z5x, 2bxr, 2bxs – hMAO-A + inhibitor + FAD – human
2z5y - hMAO-A (mutant) + inhibitor + FAD
1o5w - MAO-A + inhibitor + FAD – rat
MAO-B
1gos – hMAO-B
3po7, 2xcg, 2xfn, 2xfp, 2xfq, 2xfu, 2vz2, 2vrl, 2vrm, 2v5z, 2v60, 2v61, 2c64, 2c65, 2c66, 2c67, 2byb, 2bk3, 1s2q, 1s2y, 1s3b, 1s3e, 1oj9, 1oja, 1ojc, 1ojd – hMAO-B + inhibitor + FAD
2xfo, 2bk4, 2bk5 - hMAO-B (mutant) + inhibitor + FAD
2c72, 2c73, 2c75, 2c76 - hMAO-B (mutant) + FAD
2c70 - hMAO-B + FAD
MAO-C
3qj4 – hMAO-C + FAD
MAO-N
2vvl, 2vvm – MAO-N (mutant) + FAD – Aspergillus niger
