Monoamine oxidase

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{{STRUCTURE_1gos| PDB=1gos | SIZE=400| SCENE= |right| CAPTION=Human MAO-B dimer complex with FAD and phenyl-propenylidine derivative, [[1gos]] }}
{{STRUCTURE_1gos| PDB=1gos | SIZE=400| SCENE= |right| CAPTION=Human MAO-B dimer complex with FAD and phenyl-propenylidine derivative, [[1gos]] }}
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'''Monoamine oxidas'''e (MAO) are enzymes which catalyze the oxidation of monoamines. MAO contains FAD as co-factor. MAO-A and MAO-C are human enzymes which oxidize adrenaline, noradrenaline, serotonin and dopamine. MAO-B is a human enzyme which oxidizes benzylamine and phenylethylamine. For details on MAO-B see [[Monoamine oxidase b]].
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'''Monoamine oxidas'''e (MAO) are enzymes which catalyze the oxidation of monoamines. MAO contains FAD as co-factor.<br />
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* '''MAO-A''' and '''MAO-C''' are human enzymes which oxidize adrenaline, noradrenaline, serotonin and dopamine.<br />
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* '''MAO-B''' is a human enzyme which oxidizes benzylamine and phenylethylamine. For details on MAO-B see [[Monoamine oxidase b]].
==3D structures of monoamine oxidase ==
==3D structures of monoamine oxidase ==

Revision as of 08:40, 19 August 2014

PDB ID 1gos

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Human MAO-B dimer complex with FAD and phenyl-propenylidine derivative, 1gos
Ligands: ,
Activity: Monoamine oxidase, with EC number 1.4.3.4
Related: 1h8r
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



Monoamine oxidase (MAO) are enzymes which catalyze the oxidation of monoamines. MAO contains FAD as co-factor.

  • MAO-A and MAO-C are human enzymes which oxidize adrenaline, noradrenaline, serotonin and dopamine.
  • MAO-B is a human enzyme which oxidizes benzylamine and phenylethylamine. For details on MAO-B see Monoamine oxidase b.

Contents

3D structures of monoamine oxidase

Updated on 19-August-2014

MAO-A

2z5x, 2bxr, 2bxs – hMAO-A + inhibitor + FAD – human
2z5y - hMAO-A (mutant) + inhibitor + FAD
1o5w - MAO-A + inhibitor + FAD – rat

MAO-B

1gos – hMAO-B
3po7, 2xcg, 2xfn, 2xfp, 2xfq, 2xfu, 2vz2, 2vrl, 2vrm, 2v5z, 2v60, 2v61, 2c64, 2c65, 2c66, 2c67, 2byb, 2bk3, 1s2q, 1s2y, 1s3b, 1s3e, 1oj9, 1oja, 1ojc, 1ojd, 4a79, 4a7a – hMAO-B + inhibitor + FAD
2xfo, 2bk4, 2bk5 - hMAO-B (mutant) + inhibitor + FAD
2c72, 2c73, 2c75, 2c76 - hMAO-B (mutant) + FAD
2c70 - hMAO-B + FAD
3zyx - hMAO-B + methylene blue + FAD

MAO-C

3qj4 – hMAO-C + FAD

MAO-N

2vvl, 2vvm, 3zdn – MAO-N (mutant) + FAD – Aspergillus niger

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