Transthyretin
From Proteopedia
(Difference between revisions)
| Line 10: | Line 10: | ||
*Transthyretin | *Transthyretin | ||
| - | **[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3u2i]], [[3w3b]], [[4mrb]] – hTTR – human<br /> | + | **[[2pab]], [[1tta]], [[1ttb]], [[1etb]], [[1bmz]], [[1f41]], [[1dvq]], [[1fh2]], [[1qwh]], [[2h4e]], [[2qgb]], [[3cbr]], [[3d7p]], [[3cfm]], [[3i9p]], [[3a4d]], [[3a4e]], [[3a4f]], [[3u2i]], [[3w3b]], [[4mrb]], [[4pvl]], [[4pvn]] – hTTR – human<br /> |
| - | **[[3u2j]] – hTTR - neutron<br /> | + | **[[3u2j]], [[4pvm]] – hTTR - neutron<br /> |
**[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant) | **[[1eta]], [[1ttc]], [[1tsh]], [[2trh]], [[2try]], [[1bzd]], [[1bze]], [[1fhn]], [[1g1o]], [[1x7s]], [[2qel]], [[3dgd]], [[3did]], [[3kgs]], [[3tfb]] – hTTR (amyloidogenic mutant) | ||
**[[1ttr]] – hTTR (cardiomyapatic mutant) | **[[1ttr]] – hTTR (cardiomyapatic mutant) | ||
| - | **[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]] – hTTR (mutant) | + | **[[1bz8]], [[5ttr]], [[1f86]], [[1gko]], [[1iii]], [[1iik]], [[1ijn]], [[1sok]], [[1soq]], [[1x7t]], [[2g3x]], [[2g3z]], [[2g4e]], [[2g4g]], [[2noy]], [[3bt0]], [[3cxf]], [[3djr]], [[3djs]], [[3djt]], [[3djz]], [[3dk0]], [[3dk2]], [[3do4]], [[3gps]], [[3grb]], [[3grg]], [[3i9a]], [[3i9i]], [[4mrc]], [[4pwe]] – hTTR (mutant) |
**[[1tfp]] – TTR – chicken | **[[1tfp]] – TTR – chicken | ||
| Line 28: | Line 28: | ||
*Transthyretin binary complexes | *Transthyretin binary complexes | ||
| - | **[[1thc]], [[2h1x]], [[2h6u]] – hTTR + hydroxyaurone derivative | + | **[[1thc]], [[2h1x]], [[2h6u]] – hTTR + hydroxyaurone derivative<br /> |
| - | + | **[[4pm1]] - hTTR + estradiol derivative<br /> | |
**[[1tlm]] – hTTR + milrinone | **[[1tlm]] – hTTR + milrinone | ||
| Line 68: | Line 68: | ||
**[[3b56]] – hTTR + salicylic acid derivative<br /> | **[[3b56]] – hTTR + salicylic acid derivative<br /> | ||
**[[4hjs]], [[4hjt]], [[4hju]] – hTTR + covalent kinetic stabilizer<br /> | **[[4hjs]], [[4hjt]], [[4hju]] – hTTR + covalent kinetic stabilizer<br /> | ||
| + | **[[4pmf]] - hTTR + curcumin<br /> | ||
| + | **[[4qxv]] - hTTR + luteolin<br /> | ||
| + | **[[4qya]] - hTTR (mutant) + luteolin<br /> | ||
| + | **[[4pwf]] - hTTR (mutant) + ferulic esterase<br /> | ||
| + | **[[4pwg]], [[4pwh]], [[4qrf]] - hTTR (mutant) + caffeic esterase<br /> | ||
| + | **[[4pwi]] - hTTR (mutant) + rosamariic acid<br /> | ||
| + | **[[4pwj]], [[4pwk]] - hTTR (mutant) + propolis<br /> | ||
| + | |||
| + | *TTR ternary complexes | ||
| + | |||
| + | **[[4pme]] - hTTR + ferulic acid + curcumin<br /> | ||
*Transthyretin complexes with retinol-binding protein | *Transthyretin complexes with retinol-binding protein | ||
Revision as of 10:38, 21 June 2015
Template:STRUCTURE 1rlb
Transthyretin (TTR) is a serum carrier of the thyroid hormone thyroxine (T4) and retinol through its association with retinol-binding protein (RBP). Many small molecules bind to TTR T4-binding site. TTR is known to be associated with amyloid diseases.
3D structures of transthyretin
Updated on 21-June-2015
