Chloramphenicol acetyltransferase
From Proteopedia
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== Function == | == Function == | ||
| - | [[Chloramphenicol acetyltransferase]] (CAT) is an enzyme which makes bacteria resistant to chloramphenicol. It attaches acetyl from acetyl-CoA to chloramphenicol thus preventing it from binding to the ribosome. Additional details in [[Chloramphenicol Acetyltransferase Type III]].<ref>PMID:2187098</ref> | + | [[Chloramphenicol acetyltransferase]] (CAT) is an enzyme which makes bacteria resistant to chloramphenicol. It attaches acetyl from acetyl-CoA to chloramphenicol thus preventing it from binding to the ribosome. Additional details in [[Chloramphenicol Acetyltransferase Type III]].<ref name="Ad">PMID:2187098</ref> |
== Structural highlights == | == Structural highlights == | ||
| - | <scene name='44/449613/Cv/4'>E. coli chloramphenicol acetyltransferase III is homotrimer</scene>. In <scene name='44/449613/Cv/7'>CAT III chloramphenicol binds in a deep pocket at the interface of 2 subunits</scene> (PDB entry [[3cla]]).<ref>PMID:2187098</ref> | + | <scene name='44/449613/Cv/4'>E. coli chloramphenicol acetyltransferase III is homotrimer</scene>. In <scene name='44/449613/Cv/7'>CAT III chloramphenicol binds in a deep pocket at the interface of 2 subunits</scene> (PDB entry [[3cla]]).<ref name="Ad">PMID:2187098</ref> |
</StructureSection> | </StructureSection> | ||
== 3D Structures of Chloramphenicol acetyltransferase == | == 3D Structures of Chloramphenicol acetyltransferase == | ||
Revision as of 09:39, 14 December 2015
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3D Structures of Chloramphenicol acetyltransferase
Updated on 14-December-2015
