Poly (ADP-ribose) glycohydrolase
From Proteopedia
(Difference between revisions)
| Line 1: | Line 1: | ||
| - | <StructureSection load='' size=' | + | <StructureSection load='' size='350' side='right' caption='Structure of human poly (ADP-ribose) glycohydrolase catalytic domain complex with ADP-ribose (PDB code [[3sig]]). ' scene='59/595759/Cv/1'> |
== Function == | == Function == | ||
| Line 27: | Line 27: | ||
**[[2qty]] – mPARG 3 <br /> | **[[2qty]] – mPARG 3 <br /> | ||
**[[4a0d]], [[4b1g]] – hPARG catalytic domain (mutant) - human<br /> | **[[4a0d]], [[4b1g]] – hPARG catalytic domain (mutant) - human<br /> | ||
| + | **[[5zqy]] – hPARG Arh3 residues 19-363 <br /> | ||
*Poly (ADP-ribose) glycohydrolase complex with ADP-ribose | *Poly (ADP-ribose) glycohydrolase complex with ADP-ribose | ||
| Line 34: | Line 35: | ||
**[[4l2h]], [[5a7r]] – TtPARG (mutant) + ADP-ribose <br /> | **[[4l2h]], [[5a7r]] – TtPARG (mutant) + ADP-ribose <br /> | ||
**[[4b1h]] – hPARG catalytic domain (mutant) + ADP-ribose<br /> | **[[4b1h]] – hPARG catalytic domain (mutant) + ADP-ribose<br /> | ||
| + | **[[6d36]] – hPARG Arh3 residues 1-363 + ADP-ribose<br /> | ||
| + | **[[6d3a]] – hPARG Arh3 residues 1-363 (mutant) + ADP-ribose<br /> | ||
**[[4na0]] – mPARG catalytic domain + ADP-ribose<br /> | **[[4na0]] – mPARG catalytic domain + ADP-ribose<br /> | ||
Revision as of 09:06, 23 August 2018
| |||||||||||
3D Structures of poly (ADP-ribose) glycohydrolase
Updated on 23-August-2018
References
- ↑ Herceg Z, Wang ZQ. Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity and cell death. Mutat Res. 2001 Jun 2;477(1-2):97-110. PMID:11376691
- ↑ Virag L, Szabo C. The therapeutic potential of poly(ADP-ribose) polymerase inhibitors. Pharmacol Rev. 2002 Sep;54(3):375-429. PMID:12223530
- ↑ Slade D, Dunstan MS, Barkauskaite E, Weston R, Lafite P, Dixon N, Ahel M, Leys D, Ahel I. The structure and catalytic mechanism of a poly(ADP-ribose) glycohydrolase. Nature. 2011 Sep 4. doi: 10.1038/nature10404. PMID:21892188 doi:10.1038/nature10404
