User:Josephine Thestrup/Sandbox 1

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<scene name='81/811087/Active_site_hdac8/1'>Active</scene>
<scene name='81/811087/Active_site_hdac8/1'>Active</scene>
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<scene name='81/811087/Active_site_loop_1_s30-k36/3'> The active site loop consisting of residues 30-36 that makes the active site pocket highly malleable. It is shown in relation to an incoming ligand and the zinc ion </scene>
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<scene name='81/811087/Active_site_loop_1_s30-k36/4'>N-Terminus L1 loop</scene>
<scene name='81/811087/Asp_to_the_ligand/1'>The crucial Asp 101 interacting with the ligand at the rim of the active site</scene>
<scene name='81/811087/Asp_to_the_ligand/1'>The crucial Asp 101 interacting with the ligand at the rim of the active site</scene>

Revision as of 01:48, 8 April 2019

Histone Deacetylase 8 from Homo Sapiens

This is a default text for your page Josephine Thestrup/Sandbox 1. Click above on edit this page to modify. Be careful with the < and > signs. You may include any references to papers as in: the use of JSmol in Proteopedia [1] or to the article describing Jmol [2] to the rescue.

Human Histone Deacetylase 8 homodimer,pdb:2v5w

Drag the structure with the mouse to rotate

Contents

Introduction

Function

Structural highlights

HDAC 8 structure overview
HDAC 8 structure overview

Enzymatic mechanism

Inhibitors

Medical relevance

This is a sample scene created with SAT to by Group, and another to make of the protein. You can make your own scenes on SAT starting from scratch or loading and editing one of these sample scenes.

</StructureSection>

References

  1. Hanson, R. M., Prilusky, J., Renjian, Z., Nakane, T. and Sussman, J. L. (2013), JSmol and the Next-Generation Web-Based Representation of 3D Molecular Structure as Applied to Proteopedia. Isr. J. Chem., 53:207-216. doi:http://dx.doi.org/10.1002/ijch.201300024
  2. Herraez A. Biomolecules in the computer: Jmol to the rescue. Biochem Mol Biol Educ. 2006 Jul;34(4):255-61. doi: 10.1002/bmb.2006.494034042644. PMID:21638687 doi:10.1002/bmb.2006.494034042644

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Josephine Thestrup

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