Thioredoxin Reductase
From Proteopedia
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</StructureSection> | </StructureSection> | ||
| - | == 3D Structures of Thioredoxin Reductase == | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *Thioredoxin reductase apo | ||
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| - | **[[4ccr]] - EhTrxR - ''Entamoeba histolytica''<br /> | ||
| - | **[[5utx]] – VvTrxR – ''Vibrio vulnificus''<br /> | ||
| - | **[[5c04]], [[5id2]], [[4x0x]], [[4x1u]] – MtTrxR - ''Mycobacterium tuberculosis''<br /> | ||
| - | **[[3r9u]] – TrxR – ''Campylobacter jejuni''<br /> | ||
| - | **[[4zn0]] – TrxR – ''Methanosarcina mazei''<br /> | ||
| - | **[[4xrd]], [[4xs1]], [[4xs4]], [[4xs6]], [[5uka]], [[4xts]], [[4xra]] – TrxR (mutant) – ''Salmonella enterica''<br /> | ||
| - | **[[6bwt]] – TrxR - ''Francisella tularensis''<br /> | ||
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| - | *Thioredoxin reductase complex with FAD | ||
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| - | **[[1vdc]] – TrxR+FAD – ''Arabidopsis thaliana''<br /> | ||
| - | **[[1cl0]], [[1tde]], [[1trb]], [[4o5q]], [[4o5u]] – EcTrxR+FAD – ''Eschericia coli''<br /> | ||
| - | **[[3cty]] - TrxR+FAD – ''Thermoplasma acidophilum''<br /> | ||
| - | **[[2zbw]] – TrxR + FAD – ''Thermus thermophilus''<br /> | ||
| - | **[[5j60]] – TrxR + FAD – ''Gloeobacter violaceus''<br /> | ||
| - | **[[3ish]] - HpTrxR+FAD - ''Helicobacter pylori''<br /> | ||
| - | **[[2q7v]] - TrxR+FAD – ''Deinococcus radiodurans''<br /> | ||
| - | **[[4b1b]] - PfTrxR+FAD – ''Plasmodium falciparum''<br /> | ||
| - | **[[4jnq]] – TrxR + FDA – ''Brucella melitensis''<br /> | ||
| - | **[[4ntd]] – TrxR + FDA + glutathione – ''Steptomyces clavuligerus''<br /> | ||
| - | **[[5m5j]] – TrxR + FAD – ''Giardia duodenalis''<br /> | ||
| - | **[[5uth]] – TrxR + FAD – ''Mycobacterium smegmatis''<br /> | ||
| - | **[[5uwy]] – TrxR + FAD – ''Streptococcus pyogenes''<br /> | ||
| - | **[[5uwy]] – TrxR + FAD – ''Cypptococcus neoformans''<br /> | ||
| - | **[[6gna]], [[6gnb]], [[6gnc]] – CaTrxR + FAD – ''Clostridium acetobutylicum''<br /> | ||
| - | **[[6gnd]] – CaTrxR + FAD + Trx<br /> | ||
| - | **[[5w4c]] – TrxR + FAD – ''Cryprococcus neoformans''<br /> | ||
| - | **[[5nii]] – TrxR + FAD – ''Desulfovibrio vulgaris''<br /> | ||
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| - | *Thioredoxin reductase complex with FAD and NADP | ||
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| - | **[[1h6v]] – rTrxR (mutant)+FAD+NADPH – rat<br /> | ||
| - | **[[2nvk]] - DmTrxR+FAD+NADPH – ''Drosophila melanogaster''<br /> | ||
| - | **[[3d8x]] - yTrxR+FAD+NADPH - yeast<br /> | ||
| - | **[[1tdf]] - EcTrxR+FAD+NADPH<br /> | ||
| - | **[[1f6m]] - EcTrxR (mutant)+Trx-1+FAD+NADPH analog<br /> | ||
| - | **[[2a87]] - MtTrxR+FAD+NADPH <br /> | ||
| - | **[[2q0k]], [[2q0l]] - HpTrxR+FAD+NADPH <br /> | ||
| - | **[[4a5l]], [[4up3]], [[4cbq]] - EhTrxR+FAD+NADPH - ''Entamoeba histolyca''<br /> | ||
| - | **[[4a65]] - EhTrxR+FAD+NADPH + Au<br /> | ||
| - | **[[4ccq]] - EhTrxR+NADPH<br /> | ||
| - | **[[4gcm]] - SaTrxR+FAD+NADPH – ''Staphylococcus aureus''<br /> | ||
| - | **[[5mh4]], [[5mjk]], [[5mip]], [[5miq]], [[5mir]], [[5mis]], [[5mit]] – TrxR + FAD + NAPD – ''Lactococcus lactis''<br /> | ||
| - | **[[5usx]], [[5vt3]] – VvTrxR + FAD + NAPD - ''Vibrio vulnificus''<br /> | ||
| - | **[[6bpy]] – TrxR + FAD + NADP – ''Neosartorya fumigata''<br /> | ||
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| - | *Thioredoxin reductase 1 | ||
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| - | **[[2cfy]] – hTrxR-1+FAD – human<br /> | ||
| - | **[[2zz0]], [[2zzb]], [[2zzc]] – hTrxR-1 (mutant)+FAD<br /> | ||
| - | **[[2j3n]] – hTrxR-1+FAD+NADPH<br /> | ||
| - | **[[3qfa]], [[3qfb]] - hTrxR-1 (mutant) +FAD+ Trx<br /> | ||
| - | **[[4kpr]] - rTrxR-1 +FAD<br /> | ||
| - | **[[3ean]], [[3eao]] – rTrxR-1+FAD+NADPH<br /> | ||
| - | **[[3dh9]], [[3dgh]] – DmTrxR-1+FAD<br /> | ||
| - | **[[3itj]] – yTrxR-1+FAD <br /> | ||
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| - | *Thioredoxin reductase 2 | ||
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| - | **[[1zdl]], [[1zkq]] – mTrxR-2+FAD+NADPH – mouse<br /> | ||
| - | **[[3dgz]] – mTrxR-2 + FAD<br /> | ||
| - | **[[4owy]] – yTrxR-2 <br /> | ||
| - | **[[6a4j]] – SaTrxR-2 + FAD<br /> | ||
| - | **[[2whd]] – TrxR-2+FAD – ''Hordeum vulgare''<br /> | ||
| - | **[[4j56]], [[4j57]] - PfTrxR-2 (mutant) + Trx (mutant) +FAD<br /> | ||
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| - | *Thioredoxin reductase 3 | ||
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| - | **[[3h8q]] – hTrxR-3 glutaredoxin domain<br /> | ||
| - | **[[2lv3]] - mTrxR-3 glutaredoxin domain<br /> | ||
| - | **[[3f8d]], [[3f8p]], [[3f8r]] – TrxR-3 (mutant)+FAD – ''Sulfolobus solfataricus''<br /> | ||
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| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Revision as of 09:41, 23 February 2020
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References
- ↑ Arner ES, Holmgren A. Physiological functions of thioredoxin and thioredoxin reductase. Eur J Biochem. 2000 Oct;267(20):6102-9. PMID:11012661
- ↑ Prasad R, Chan LF, Hughes CR, Kaski JP, Kowalczyk JC, Savage MO, Peters CJ, Nathwani N, Clark AJ, Storr HL, Metherell LA. Thioredoxin Reductase 2 (TXNRD2) mutation associated with familial glucocorticoid deficiency (FGD). J Clin Endocrinol Metab. 2014 Aug;99(8):E1556-63. doi: 10.1210/jc.2013-3844. Epub, 2014 Mar 6. PMID:24601690 doi:http://dx.doi.org/10.1210/jc.2013-3844
- ↑ Fritz-Wolf K, Kehr S, Stumpf M, Rahlfs S, Becker K. Crystal structure of the human thioredoxin reductase-thioredoxin complex. Nat Commun. 2011 Jul 12;2:383. doi: 10.1038/ncomms1382. PMID:21750537 doi:10.1038/ncomms1382
