Rho-associated protein kinase
From Proteopedia
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**[[2f2u]] – hROCK2 kinase domain <br /> | **[[2f2u]] – hROCK2 kinase domain <br /> | ||
**[[4wot]], [[4l6q]], [[2h9v]], [[5u7q]], [[5u7r]], [[6ed6]], [[7jnt]], [[7jov]] – hROCK2 kinase domain + inhibitor <br /> | **[[4wot]], [[4l6q]], [[2h9v]], [[5u7q]], [[5u7r]], [[6ed6]], [[7jnt]], [[7jov]] – hROCK2 kinase domain + inhibitor <br /> | ||
| - | **[[6p5m]] – hROCK2 kinase domain + anti-cancer inhibitor <br /> | + | **[[6p5m]], [[6p5p]] – hROCK2 kinase domain + anti-cancer inhibitor <br /> |
**[[2rov]] – hROCK2 split PH domain - NMR<br /> | **[[2rov]] – hROCK2 split PH domain - NMR<br /> | ||
**[[2row]] – hROCK2 C1 domain - NMR<br /> | **[[2row]] – hROCK2 C1 domain - NMR<br /> | ||
Revision as of 09:36, 16 February 2022
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3D structures of Rho-associated protein kinase
Updated on 16-February-2022
References
- ↑ Smith AL, Dohn MR, Brown MV, Reynolds AB. Association of Rho-associated protein kinase 1 with E-cadherin complexes is mediated by p120-catenin. Mol Biol Cell. 2012 Jan;23(1):99-110. doi: 10.1091/mbc.E11-06-0497. Epub 2011 Oct, 26. PMID:22031287 doi:http://dx.doi.org/10.1091/mbc.E11-06-0497
- ↑ Schofield AV, Bernard O. Rho-associated coiled-coil kinase (ROCK) signaling and disease. Crit Rev Biochem Mol Biol. 2013 Jul-Aug;48(4):301-16. doi:, 10.3109/10409238.2013.786671. Epub 2013 Apr 19. PMID:23601011 doi:http://dx.doi.org/10.3109/10409238.2013.786671
- ↑ Honjo M, Tanihara H, Inatani M, Kido N, Sawamura T, Yue BY, Narumiya S, Honda Y. Effects of rho-associated protein kinase inhibitor Y-27632 on intraocular pressure and outflow facility. Invest Ophthalmol Vis Sci. 2001 Jan;42(1):137-44. PMID:11133858
- ↑ Green J, Cao J, Bandarage UK, Gao H, Court J, Marhefka C, Jacobs M, Taslimi P, Newsome D, Nakayama T, Shah S, Rodems S. Design, Synthesis, and Structure-Activity Relationships of Pyridine-Based Rho Kinase (ROCK) Inhibitors. J Med Chem. 2015 Jun 12. PMID:26039570 doi:http://dx.doi.org/10.1021/acs.jmedchem.5b00424
