TRNA-guanine transglycosylase
From Proteopedia
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==3D structures of tRNA-guanine transglycosylase== | ==3D structures of tRNA-guanine transglycosylase== | ||
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[[tRNA-guanine transglycosylase 3D structures]] | [[tRNA-guanine transglycosylase 3D structures]] | ||
</StructureSection> | </StructureSection> | ||
| - | ==3D structures of tRNA-guanine transglycosylase== | ||
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| - | Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} | ||
| - | {{#tree:id=OrganizedByTopic|openlevels=0| | ||
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| - | *tRNA-guanine transglycosylase | ||
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| - | **[[6h42]] – hTGT catalytic subunit – human<BR /> | ||
| - | **[[6fv5]] – mTGT non-catalytic subunit – mouse<BR /> | ||
| - | **[[7b2i]] – mTGT catalytic + accessory subunits (mutant)<BR /> | ||
| - | **[[6h62]] – mTGT catalytic subunit <BR /> | ||
| - | **[[1pud]], [[1p0d]], [[4pun]] – ZmTGT – ''Zymomonas mobilis''<BR /> | ||
| - | **[[1wkd]], [[1wke]], [[1wkf]], [[1ozm]], [[2oko]], [[2z1v]], [[2nso]], [[3bl3]], [[3hfy]], [[4gd0]], [[4h6e]], [[3unt]], [[3uvi]], [[4dxx]], [[4dy1]], [[4htb]], [[4ipp]], [[4jbr]], [[4l56]], [[4q8m]], [[4q8n]], [[6h7c]], [[6ygm]], [[6yry]], [[6yfx]], [[6yfw]], [[6z0d]], [[7a0b]], [[7a3v]], [[7a3x]], [[7a4k]], [[7a4x]], [[7a6d]], [[7a9e]], [[7adn]], [[7apm]], [[7apl]] – ZmTGT (mutant)<BR /> | ||
| - | **[[2ash]] – TGT – ''Thermotoga maritima''<BR /> | ||
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| - | *tRNA-guanine transglycosylase complexes | ||
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| - | **[[6h45]] – hTGT + queuine<BR /> | ||
| - | **[[7nq4]] – hTGT catalytic + accessory subunits + RNA<BR /> | ||
| - | **[[1p0e]] – ZmTGT + preQ1<BR /> | ||
| - | **[[1efz]], [[1pxg]], [[1ozq]], [[2z1x]], [[2nqz]], [[3bld]], [[4gcx]], [[4e2v]] – ZmTGT (mutant) + preQ1<BR /> | ||
| - | **[[3bll]] – ZmTGT (mutant) + preQ1 derivative<BR /> | ||
| - | **[[1p0b]], [[2qii]] – ZmTGT + preQ0<BR /> | ||
| - | **[[2pwv]] – ZmTGT (mutant) + preQ0<BR /> | ||
| - | **[[3blo]], [[4hqv]], [[4hsh]], [[4hvx]] – ZmTGT (mutant) + queuine<BR /> | ||
| - | **[[1enu]], [[1f3e]] – ZmTGT + aminophthalhydrazide<BR /> | ||
| - | **[[1r5y]], [[1q4w]], [[1q63]], [[1q65]], [[1q66]], [[1s38]], [[1s39]], [[1y5v]], [[1y5w]], [[1y5x]], [[2bbf]], [[2qzr]], [[3eos]], [[3eou]], [[3gc4]], [[1k4g]], [[1k4h]], [[3gc5]], [[3ge7]], [[4puj]], [[4puk]], [[4q4o]], [[4q4p]], [[4q4q]], [[4q4r]], [[4q4s]], [[4q8t]], [[4q4u]], [[4q8v]], [[4q8w]], [[5jxq]], [[5jsw]], [[5jxq]], [[5lpo]], [[5lpp]], [[5lpq]], [[5lps]], [[5lpt]], [[3c2y]], [[5i00]], [[5i02]], [[5i03]], [[5i06]], [[5i07]], [[5jgm]], [[5jgo]], [[5jsv]], [[6rkq]], [[6rkt]] – ZmTGT + quinazoline inhibitor<BR /> | ||
| - | **[[4pul]], [[4pum]], [[4q8o]], [[4q8p]], [[4q8q]], [[6fmn]], [[6fpu]], [[6yh3]], [[6h7c]], [[6ygk]], [[6ygl]], [[6ygo]] [[6ygp]], [[6ygs]], [[6ygy]], [[6ygx]], [[6ygw]], [[6ygz]], [[6yh1]], [[6ygr]], [[6yhe]], [[6yiq]], [[6yyz]], [[6yhd]] – ZmTGT (mutant) + quinazoline inhibitor<BR /> | ||
| - | **[[4q4m]] – ZmTGT + triazine inhibitor<BR /> | ||
| - | **[[5egr]], [[5sw3]], [[5v3c]], [[5utj]] – ZmTGT + inhibitor<BR /> | ||
| - | **[[6yh2]] – ZmTGT (mutant) + inhibitor<BR /> | ||
| - | **[[1n2v]], [[2z1w]] – ZmTGT + pyridazine derivative<BR /> | ||
| - | **[[5sw3]], [[6fso]] – ZmTGT + pyridine derivative<BR /> | ||
| - | **[[5utj]] – ZmTGT + azapurine derivative<BR /> | ||
| - | **[[5v3c]] – ZmTGT + cyclohexane derivative<BR /> | ||
| - | **[[1q2r]], [[1q2s]] – ZmTGT + RNA<BR /> | ||
| - | **[[5n6f]] – ZmTGT + guanine<BR /> | ||
| - | **[[2pot]], [[2pwu]], [[4h7z]] – ZmTGT (mutant) + guanine<BR /> | ||
| - | **[[5uti]] – ZmTGT + canavanine<BR /> | ||
| - | **[[2z7k]], [[3rr4]], [[3tll]], [[4fr6]], [[4fsa]], [[4fr1]], [[4fps]], [[4gi4]], [[4giy]], [[4gkt]], [[4kwo]], [[4lbu]], [[4leq]], [[5i09]] – ZmTGT + benzoguanine derivative<BR /> | ||
| - | **[[5j9m]], [[5j9n]], [[5j9o]], [[5jt5]], [[5jt6]], [[5jt7]] – ZmTGT + benzoimidazole derivative<BR /> | ||
| - | **[[3s1g]], [[3sm0]], [[4gg9]], [[4gh1]], [[4gh3]], [[4ghr]] – ZmTGT + benzohypoxanthine derivative<BR /> | ||
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| - | *Archaebacterial tRNA-guanine transglycosylase | ||
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| - | **[[1iq8]] – PhATGT – ''Pyrococcus horikoshii''<BR /> | ||
| - | **[[1it7]] – PhATGT + guanine<BR /> | ||
| - | **[[1it8]] – PhATGT + preQ0<BR /> | ||
| - | **[[1j2b]] – PhATGT + tRNA-Val<BR /> | ||
| - | }} | ||
== References == | == References == | ||
<references/> | <references/> | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
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References
- ↑ Nonekowski ST, Garcia GA. tRNA recognition by tRNA-guanine transglycosylase from Escherichia coli: the role of U33 in U-G-U sequence recognition. RNA. 2001 Oct;7(10):1432-41. PMID:11680848
- ↑ Sabina J, Soll D. The RNA-binding PUA domain of archaeal tRNA-guanine transglycosylase is not required for archaeosine formation. J Biol Chem. 2006 Mar 17;281(11):6993-7001. Epub 2006 Jan 10. PMID:16407303 doi:http://dx.doi.org/M512841200
- ↑ Brenk R, Stubbs MT, Heine A, Reuter K, Klebe G. Flexible adaptations in the structure of the tRNA-modifying enzyme tRNA-guanine transglycosylase and their implications for substrate selectivity, reaction mechanism and structure-based drug design. Chembiochem. 2003 Oct 6;4(10):1066-77. PMID:14523925 doi:10.1002/cbic.200300644
