Peptidyl-tRNA hydrolase
From Proteopedia
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'''Peptidyl-tRNA hydrolase''' (PTH) is a bacterial enzyme which cleaves peptidyl-tRNA to free peptide and tRNA<ref>PMID:16849786</ref>. PTH catalyzes the reaction in cases of aborted translation for recycling the tRNA for further rounds of protein synthesis. PTH is essential for bacterial viability.rew)]]. | '''Peptidyl-tRNA hydrolase''' (PTH) is a bacterial enzyme which cleaves peptidyl-tRNA to free peptide and tRNA<ref>PMID:16849786</ref>. PTH catalyzes the reaction in cases of aborted translation for recycling the tRNA for further rounds of protein synthesis. PTH is essential for bacterial viability.rew)]]. | ||
| - | See also [[Peptidyl-tRNA 2, mitochondrial (Hebrew)]]. | + | See also [[Peptidyl-tRNA hydrolase 2, mitochondrial (Hebrew)]]. |
== Structural highlights == | == Structural highlights == | ||
Current revision
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3D Structures of peptidyl-tRNA hydrolase
Updated on 05-January-2025
References
- ↑ Das G, Varshney U. Peptidyl-tRNA hydrolase and its critical role in protein biosynthesis. Microbiology. 2006 Aug;152(Pt 8):2191-5. PMID:16849786 doi:http://dx.doi.org/10.1099/mic.0.29024-0
- ↑ Ito K, Murakami R, Mochizuki M, Qi H, Shimizu Y, Miura KI, Ueda T, Uchiumi T. Structural basis for the substrate recognition and catalysis of peptidyl-tRNA hydrolase. Nucleic Acids Res. 2012 Aug 25. PMID:22923517 doi:10.1093/nar/gks790
