User:Tilman Schirmer/Sandbox 202
From Proteopedia
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<scene name='User:Tilman_Schirmer/Sandbox_202/Blrp1_active_site_ligand_hoh/2'>Active site + ligand + Mn + HOH</scene> | <scene name='User:Tilman_Schirmer/Sandbox_202/Blrp1_active_site_ligand_hoh/2'>Active site + ligand + Mn + HOH</scene> | ||
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Revision as of 08:50, 15 July 2009
C-di-GMP specific phosphodiesterases
YukI
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is a dimer with each protomer composed of an , a long , and a .
The is situated at the C-terminal end of the central β-barrel of the EAL domain (with TIM fold). The residues of the active site are well conserved, including E33 and L35 of the EAL signature motif.
The is bound flat upon the actve site with the divalent metal (here Ca++) being sandwiched between binding site and c-di-GMP.
BlrP1
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