4kgb

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Template:STRUCTURE 4kgb

Contents

Structure of succinyl-CoA: 3-ketoacid CoA transferase from Drosophila melanogaster

Template:ABSTRACT PUBMED 24100554

Function

[Q9W058_DROME] Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate (By similarity).[PIRNR:PIRNR000858]

About this Structure

4kgb is a 2 chain structure with sequence from Drosophila melanogaster. Full crystallographic information is available from OCA.

Reference

  • Zhang M, Xu HY, Wang YC, Shi ZB, Zhang NN. Structure of succinyl-CoA:3-ketoacid CoA transferase from Drosophila melanogaster. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2013 Oct;69(Pt 10):1089-93., doi: 10.1107/S1744309113024986. Epub 2013 Sep 28. PMID:24100554 doi:http://dx.doi.org/10.1107/S1744309113024986

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