Annexin
From Proteopedia
Annexins are proteins which make a membrane scaffold. They bind negatively charged phospholipids and contain a 70 amino acid long annexin repeat. They consist of 2 domains - the C-terminal core and the N-terminal head. Annexins divide into species and are numbered from I to XII. Annexin V is the most abundant scaffolding protein. Annexin E1 (AnE1) is associated with tubulin in trophozoites of Giardia lamblia and forms local slubs in the flagella. In the annexin image calcium ions are shown as green balls.
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3D structures of annexin
Updated on 24-August-2014
Annexin I
2q4c, 1ycn - AnI - Arabidopsis thaliana
1mcx, 1hm6 - pAnI - pig
1qls - pAnI head+calgizzarrin
1bo9 - hAnI head - human NMR
1ain - hAnI
4mdv, 4mdu – AnI + Ca – Schistosoma mansoni
Annexin II
2hyu, 2hyv - hAnII+heparin oligosaccharide
2hyw, 1xjl - hAnII+Ca
1w7b - hAnII
1bt6 - hAnII head+calpactin light chain
Annexin III
Annexin IV
2zhi, 2zhj, rAnIV+Na - rat
2zoc - hAnIV
1i4a - cAnIV (mutant) - cow
1aow, 1ann - cAnIV
Annexin V
2ie6, 2ie7, rAnV
1n41, 1n42, 1n44, 2h0k, 2h0l, 2h0m, 1bc0, 1bc1, 1bc3, 1bcw, 1bcy, 1bcz - rAnV (mutant)
1g5n - rAnV+ heparin oligosaccharide
1a8a, 1a8b - rAnV+phospholipid analog
2ran - rAnV+Ca
1yii – chAnV+Ca – chicken
1yj0 - chAnV+Zn
1ala - ChAnV
1hak - hAnV+K-201
1sav - hAnV (thioproline)
1hvd, 1hve, 1hvf, 1hvg - hAnV (mutant)
1anw, 1avh, 1avr - hAnV
1anx - hAnV+Ca
2xo2 – hAnV + Ca + azidohomoalanine
2xo3 - hAnV + Ca + homopropargylglycine
Annexin VI
1m9i - hAnVI (mutant)
1avc - cAnVI+Ca
Annexin VIII
1w3w - hAnVIII
1w45 - hAnVIII (mutant)
Annexin XII
1dm5 - HvAnXII (mutant) - Hydra vulgaris
1aei - HvAnXII
Annexin E1
3chj – GlAnE1 – Giardia lamblia
3chk, 3chl – GlAnE1 + cation
Other annexins
1dk5 - An24 - Capsicom annuum
3brx - coAnGH1+Ca - cotton
1n00 - coAnGH1
