Catenin

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Contents 1 Function 2 3D Structures of Catenin 3 References

Function

Catenins (CTN) are proteins which make complexes with cadherin.

• α-CTN links cadherin (CDH) and α-actinin, it is encoded by 3 genes: α-E-CTN (epithelial), α-T-CTN (membrane bound), and α-N-CTN (neuronal).
  
• β-CTN is a subunit of the cadherin complex. It contains Armadillo repeats which are a pair of helices forming hairpin structure.
  
• γ-CTN (or plakoglobin) is a component of desmosomes and contains armadillo repeats.
  
• δ-CTN is expressed in the brain and contains 10 armadillo repeats.
  
• p120 CTN is another member of the CTN family.
  

^[1]

3D Structures of Catenin

Updated on 29-November-2015

References

1. ↑ Weis WI, Nelson WJ. Re-solving the cadherin-catenin-actin conundrum. J Biol Chem. 2006 Nov 24;281(47):35593-7. Epub 2006 Sep 27. PMID:17005550 doi:http://dx.doi.org/10.1074/jbc.R600027200