2h89

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Template:STRUCTURE 2h89

Avian Respiratory Complex II with Malonate Bound

Template:ABSTRACT PUBMED 16935256

About this Structure

2H89 is a Protein complex structure of sequences from Gallus gallus. Full crystallographic information is available from OCA.

Reference

Crystallographic studies of the binding of ligands to the dicarboxylate site of Complex II, and the identity of the ligand in the "oxaloacetate-inhibited" state., Huang LS, Shen JT, Wang AC, Berry EA, Biochim Biophys Acta. 2006 Sep-Oct;1757(9-10):1073-83. Epub 2006 Jul 12. PMID:16935256

3-nitropropionic acid is a suicide inhibitor of mitochondrial respiration that, upon oxidation by complex II, forms a covalent adduct with a catalytic base arginine in the active site of the enzyme., Huang LS, Sun G, Cobessi D, Wang AC, Shen JT, Tung EY, Anderson VE, Berry EA, J Biol Chem. 2006 Mar 3;281(9):5965-72. Epub 2005 Dec 21. PMID:16371358

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