1qm2

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Template:STRUCTURE 1qm2

Contents

HUMAN PRION PROTEIN FRAGMENT 121-230

Template:ABSTRACT PUBMED 10618385

Disease

Known disease associated with this structure: Creutzfeldt-Jakob disease OMIM:[176640], Gerstmann-Straussler disease OMIM:[176640], Huntington disease-like 1 OMIM:[176640], Insomnia, fatal familial OMIM:[176640], Prion disease with protracted course OMIM:[176640]

About this Structure

1QM2 is a 1 chain structure of sequence from Homo sapiens. The May 2008 RCSB PDB Molecule of the Month feature on Prions by David S. Goodsell is 10.2210/rcsb_pdb/mom_2008_5. Full experimental information is available from OCA.

Reference

  • Zahn R, Liu A, Luhrs T, Riek R, von Schroetter C, Lopez Garcia F, Billeter M, Calzolai L, Wider G, Wuthrich K. NMR solution structure of the human prion protein. Proc Natl Acad Sci U S A. 2000 Jan 4;97(1):145-50. PMID:10618385

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