3c1k

From Proteopedia

proteopedia linkproteopedia link

Template:STRUCTURE 3c1k

Contents 1 Crystal structure of thrombin in complex with inhibitor 15 2 About this Structure 3 See Also 4 Reference

Crystal structure of thrombin in complex with inhibitor 15

Template:ABSTRACT PUBMED 18291642

About this Structure

3c1k is a 2 chain structure of Hirudin with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Hirudin

Reference

• Isaacs RC, Solinsky MG, Cutrona KJ, Newton CL, Naylor-Olsen AM, McMasters DR, Krueger JA, Lewis SD, Lucas BJ, Kuo LC, Yan Y, Lynch JJ, Lyle EA. Structure-based design of novel groups for use in the P1 position of thrombin inhibitor scaffolds. Part 2: N-acetamidoimidazoles. Bioorg Med Chem Lett. 2008 Mar 15;18(6):2062-6. Epub 2008 Jan 30. PMID:18291642 doi:10.1016/j.bmcl.2008.01.098