2qhc

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Image:2qhc.png

Template:STRUCTURE 2qhc

The Influence of I47A Mutation on Reduced Susceptibility to the Protease Inhibitor Lopinavir

Template:ABSTRACT PUBMED 18560011

About this Structure

2QHC is a 2 chains structure of sequences from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

  • Saskova KG, Kozisek M, Lepsik M, Brynda J, Rezacova P, Vaclavikova J, Kagan RM, Machala L, Konvalinka J. Enzymatic and structural analysis of the I47A mutation contributing to the reduced susceptibility to HIV protease inhibitor lopinavir. Protein Sci. 2008 Sep;17(9):1555-64. Epub 2008 Jun 17. PMID:18560011 doi:10.1110/ps.036079.108

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