4a7i

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Template:STRUCTURE 4a7i

Contents

Factor Xa in complex with a potent 2-amino-ethane sulfonamide inhibitor

Template:ABSTRACT PUBMED 22190348

About this Structure

4a7i is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Nazare M, Matter H, Will DW, Wagner M, Urmann M, Czech J, Schreuder H, Bauer A, Ritter K, Wehner V. Fragment deconstruction of small, potent factor xa inhibitors: exploring the superadditivity energetics of fragment linking in protein-ligand complexes. Angew Chem Int Ed Engl. 2012 Jan 23;51(4):905-11. doi:, 10.1002/anie.201107091. Epub 2011 Dec 21. PMID:22190348 doi:10.1002/anie.201107091

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