3i1y

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Image:3i1y.png

Template:STRUCTURE 3i1y

Contents

Crystal Structure of soluble epoxide Hydrolase

Template:ABSTRACT PUBMED 19746975

Disease

Known disease associated with this structure: Hypercholesterolemia, familial, due to LDLR defect, modifier of OMIM:[132811]

About this Structure

3I1Y is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Eldrup AB, Soleymanzadeh F, Taylor SJ, Muegge I, Farrow NA, Joseph D, McKellop K, Man CC, Kukulka A, De Lombaert S. Structure-based optimization of arylamides as inhibitors of soluble epoxide hydrolase. J Med Chem. 2009 Oct 8;52(19):5880-95. PMID:19746975 doi:10.1021/jm9005302

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